Results 51 to 60 of about 10,040 (298)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
An IoT System for Remote Monitoring of Patients at Home
Applied Sciences, 2017 Application areas that utilize the concept of IoT can be broadened to healthcare or remote monitoring areas. In this paper, a remote monitoring system for patients at home in IoT environments is proposed, constructed, and evaluated through several ...
KeeHyun Park, Joonsuu Park, JongWhi Lee
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Restless bandit marginal productivity indices II: multiproject case and scheduling a multiclass make-to-order/-stock M/G/1 queue [PDF]
, 2004 This paper develops a framework based on convex optimization and economic ideas to formulate and solve approximately a rich class of dynamic and stochastic resource allocation problems, fitting in a generic discrete-state multi-project restless bandit ...
Niño-Mora, José, Niño Mora, José
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Network real-time scheduling algorithm based on multi-feature dynamic priority
Tongxin xuebao, 2020 Real-time task scheduling system structure and task model were proposed aiming at the network real-time scheduling problem.The task degree of urgency was defined by considering the deadline of task,execution time and interval time between works.The task ...
Xun SU +5 more
doaj +2 more sources
Dynamic Scheduling for High Throughput Satellites Employing Priority Code Scheme
IEEE Access, 2015 Based on the use of multi-beams, high throughput satellites (HTSs) provide high data rates to a large number of users. In this context, the distribution of frequency resources among multi-beams plays an important role.
Lilian Del Consuelo Hernandez Ruiz Gaytan +3 more
doaj +1 more source
Efficient Schedulability Test for Dynamic-Priority Scheduling of Mixed-Criticality Real-Time Systems [PDF]
ACM Transactions on Embedded Computing Systems, 2017 Systems in many safety-critical application domains are subject to certification requirements. In such a system, there are typically different applications providing functionalities that have varying degrees of criticality. Consequently, the certification requirements for functionalities at these different criticality levels are also varying, with very
Xiaozhe Gu, Arvind Easwaran
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source