Results 141 to 150 of about 18,365,131 (347)
Tailored ensembles of neural networks optimize sensitivity to stimulus statistics
The dynamic range of stimulus processing in living organisms is much larger than a single neural network can explain. For a generic, tunable spiking network we derive that while the dynamic range is maximal at criticality, the interval of discriminable ...
Levina, Anna +3 more
core +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Experimental studies of nonlinear properties of low-power radio-frequency amplifiers similar to those used in 4G/5G mobile communication equipment of the FR1 frequency range are carried out.
V. I. Mordachev +5 more
doaj +1 more source
Precise Implementation of CDTA
The Current Differencing Transconductance Amplifier (CDTA) is a popular active building block for analog signal processing. Since it is not available as a commercial IC, most of the CDTA applications are verified only via simulations or the CDTA is ...
Dalibor Biolek, Jiri Vavra
doaj +1 more source
Signal phase switches offer greater dynamic range [PDF]
Circuit, placed in the signal path of a closed-loop receiver to modulate telemetered data in the 10-MHz spectrum, improves signal-to-noise ratio by 3 db in a communication receiver.
Crow, R. B.
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Red fluorescent cAMP indicator with increased affinity and expanded dynamic range
cAMP is one of the most important second messengers in biological processes. Cellular dynamics of cAMP have been investigated using a series of fluorescent indicators; however, their sensitivity was sub-optimal for detecting cAMP dynamics at a low ...
Yusaku Ohta +3 more
semanticscholar +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
In artificial visual systems, optimizing the dynamic range (DR) of optoelectronic synapses is essential for achieving robust and environment‐adaptive perception.
Zhiyao Zheng +12 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

