Results 71 to 80 of about 1,267,111 (263)

High-Density Microfluidic Chip with Vertical Structure for Digital PCR

open access: yesSensors
Digital PCR, as a nucleic acid absolute quantification method at the single-molecule level, has been widely applied in early cancer screening, single-cell analysis, and other biomedical fields. However, existing digital PCR methods still suffer from high
Peng Sun   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

dynamic range

open access: yes, 2014
Citation: 'dynamic range' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01874 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +2 more sources

Design of a high-precision ADC for the application of monitoring electric power in power grid

open access: yesDianzi Jishu Yingyong, 2018
In order to meet the needs of electric power system monitoring, a 3 bit 5 order sigma-delta ADC is designed and implemented. The measurement results show that the dynamic range of the system is higher than 100 dB and the effective bit is greater than 16 ...
Chen Xing   +3 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Detector of asynchronous pulse noise in conditions of additive mixture of uncorrelated and discrete in range correlated gaussian noise

open access: yesТехнологія та конструювання в електронній апаратурі
One of the main requirements for radio engineering systems is their ability to withstand high levels of noise in complex, changing and a priori unknown noise environments.
Igor Tsevukh, Anastasia Sakovich
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Review and Perspective on Reverse Leakage Current Mitigation for Extended PDR in Fully Integrated RF Energy Harvesting System

open access: yesIEEE Access
Body Sensor Network (BSN) devices facilitate real-time health monitoring, however, these devices are battery-powered and have a finite lifespan. Radio Frequency energy harvesting (RFEH) systems have emerged as a viable solution to enable batteryless and ...
Yan Joe Cheong   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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