Results 31 to 40 of about 314,928 (308)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Correlation between per-well average dynamic reserves and initial absolute open flow potential (AOFP) for large gas fields in China and its application

open access: yesPetroleum Exploration and Development, 2018
Based on performance data of over 600 wells in 32 large gas fields of different types in China, the correlation is established between per-well average dynamic reserves (G¯) and average initial absolute open flow potential (q¯IAOF) of each field, and its
Xizhe LI   +8 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Analysis on the ecosystem service protection effect of national nature reserve in Qinghai-Tibetan Plateau from weight perspective

open access: yesEcological Indicators, 2022
The analysis of the protection effect from the perspective of ecosystem service function (ESF) is an important basis for proposing optimal management strategies in nature reserves.
Xiaoyao Zhang, Sisi Li, Hu Yu
doaj   +1 more source

Fisheries and biodiversity benefits of using static versus dynamic models for designing marine reserve networks [PDF]

open access: yes, 2015
Marine reserves are widely used to manage for the potentially conflicting objectives of conserving biodiversity and improving fisheries. The fisheries and conservation benefits of alternative reserve designs would ideally be assessed using dynamic models,
Beger, M   +9 more
core   +1 more source

Model-free Adaptive Hysteresis for Dynamic Bandwidth Reservation [PDF]

open access: yes2007 15th International Symposium on Modeling, Analysis, and Simulation of Computer and Telecommunication Systems, 2007
Dynamic bandwidth reservation refers to the process of dynamically updating the bandwidth allocation to a connection between two network end points on the basis of actual aggregate traffic demand of the connection. We assume a scenario in which bandwidth updates for the connection should not be performed too frequently and the frequency of updates are ...
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Replacing Manual Operation with Bio-Automation II: Construction of a Biological Digestion Gene Circuit to Eliminate the Interference of Food Matrices in the Rapid Detection of Heavy Metals

open access: yesFoods
Food matrices such as phytic acid, starch, and proteins can chelate heavy metals, acting as stabilizers that significantly hinder accurately detecting heavy metal contamination.
Shiqi Xia   +5 more
doaj   +1 more source

Distributed Secondary Frequency Control through MTDC Transmission Systems

open access: yes, 2015
In this paper, we present distributed controllers for sharing primary and secondary frequency control reserves for asynchronous AC transmission systems, which are connected through a multi-terminal HVDC grid.
Andersson, Göran   +4 more
core   +2 more sources

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