Results 111 to 120 of about 4,948 (274)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

An Efficient Symmetric Searchable Encryption Scheme for Cloud Storage [PDF]

Journal of Internet Services and Information Security, 2017
Symmetric searchable encryption for cloud storage enables users to retrieve the documents they want in a privacy-preserving way, which has become a hotspot of research.
Xiuxiu Jiang, Xinrui Ge, Jia Yu, Fanyu Kong, Xiangguo Cheng, Rong Hao   +5 more
doaj  

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Efficient Access Control for Video Anomaly Detection Using ABE-Based User-Level Revocation with Ciphertext and Index Updates

Applied Sciences
With the widespread deployment of video surveillance systems, effective access control is essential to enhance the accuracy and security of video anomaly detection. This paper proposes a Searchable and Revocable Attribute-Based Encryption scheme (ABE-RS)
Lu Jiang, Jielu Yan, Weizhi Xian, Xuekai Wei, Xiaofeng Liao   +4 more
doaj   +1 more source

Dynamic Searchable Encryption with Small Client Storage

Proceedings 2020 Network and Distributed System Security Symposium, 2020
Ioannis Demertzis, Javad Ghareh Chamani, Dimitrios Papadopoulos, Charalampos Papamanthou   +3 more
openaire   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

d-DSE: Distinct Dynamic Searchable Encryption Resisting Volume Leakage in Encrypted Databases

ArXiv & 33rd USENIX Security Symposium 2024
Comment: 23pages, 13 figures, will be published in USENIX Security ...
Liu, Dongli, Wang, Wei, Xu, Peng, Yang, Laurence T., Luo, Bo, Liang, Kaitai   +5 more
openaire   +3 more sources

Software Grand Exposure: SGX Cache Attacks Are Practical

, 2017
Side-channel information leakage is a known limitation of SGX. Researchers have demonstrated that secret-dependent information can be extracted from enclave execution through page-fault access patterns.
Brasser, Ferdinand, Capkun, Srdjan, Dmitrienko, Alexandra, Kostiainen, Kari, Müller, Urs, Sadeghi, Ahmad-Reza   +5 more
core