Results 181 to 190 of about 2,018 (260)

Complementary Sensitivity of Fixed‐Time and Fixed‐Oscillation Regimes to Exchange and Structural Disorder in the Human Brain Revealed Using Oscillating‐Gradient Diffusion MRI With Ultra‐Strong Gradients

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 6, Page 3429-3444, June 2026.
ABSTRACT Purpose Oscillating‐gradient spin‐echo (OGSE) diffusion MRI probes cell geometry and membrane integrity through the frequency‐dependence of kurtosis, but prior studies have reported inconsistent findings depending on how frequency is varied. We compared frequency‐dependent kurtosis in the human brain under two regimes: varying frequency with ...
Dongsuk Sung   +8 more
wiley   +1 more source

A Comparative Study of Context‐Aware Modeling Approaches for Specific Heat Load Profiles for Residential Consumers in District Heating Simulations

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 2, June 2026.
ABSTRACT Accurate, time‐resolved heat load profiles are essential for realistic district heating simulations, enabling optimized network operation and long‐term transformation planning. In this work, we systematically evaluate modeling approaches for generating such profiles, comparing data‐driven methods (e.g., regression and machine learning) with ...
Johanna Heidrich   +2 more
wiley   +1 more source

Detection of protein symmetry and structural rearrangements using secondary structure elements

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Many proteins exhibit a degree of internal symmetry in their tertiary structure, including circular permutations. These characteristics play an important role in terms of the functional robustness of proteins against mutations, and are pivotal for the study of protein function and evolution.
Runfeng Lin, Sebastian E. Ahnert
wiley   +1 more source

Investigating the role of a conserved hydrophobic pocket of gp41 in the anti‐HIV activity of fusion inhibitors

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Membrane fusion between HIV and host cells requires interaction between the N‐terminal and C‐terminal repeat regions (NHR and CHR) of the gp41 envelope subunit. A deep hydrophobic pocket (HP) on the surface of NHR is considered crucial in this interaction.
Daniel Polo‐Megías   +9 more
wiley   +1 more source

E2EE enhanced patient-centric blockchain-based system for EHR management. [PDF]

open access: yesPLoS One
Haddad A   +5 more
europepmc   +1 more source

Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Minimal bacterial cells such as JCVI‐Syn3A provide a powerful system for uncovering the essential mechanisms of chromosome organization and segregation. Lacking canonical systems such as Min and ParABS, JCVI‐Syn3A relies primarily on structural maintenance of chromosomes (SMC) protein complexes for partitioning.
Andrew K. Maytin   +2 more
wiley   +1 more source

Analysis of the heterogenous structural states of the hexameric ATPase PilU of the type IV pili from Vibrio cholerae

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Type IV pili (T4P) mediate surface motility, host interactions, and DNA uptake through cycles of extension and retraction. While the primary retraction ATPase PilT has been extensively characterized, its homolog PilU remains less well understood despite being demonstrated as a PilT‐dependent retraction ATPase.
Yirui Guo   +9 more
wiley   +1 more source

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