Results 101 to 110 of about 5,704,667 (268)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Solution of Time Fractional SIQR Epidemic System and Research with Respect to the Fractional Order

Fractal and Fractional
This article deals with the global existence and uniqueness of solutions to a fractional-order SIQR epidemic model, alongside its intricate chaotic and complex dynamics as functions of the fractional order.
Pingping Li, Zhen Wang, Gongsheng Li
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Dinámica de la frecuencia del Sistema InterconectadDinámica Interconectado Ecuador-Colombia; Dinamic of the frequency of the interconected system Ecuador- Colombia

Revista Científica de Ingeniería Energética, 2011
En el presente trabajo se propone un procedimiento para estudiar la dinámica de lafrecuencia del sistema interconectado Ecuador-Colombia, ante la salida de unidadesgeneradoras cuando no se dispone de la información necesaria del sistema el ...
Marcelo Arias Castañeda, Antonio Martínez García   +1 more
doaj  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Static and dynamic performance assessment of a grid-connected solar photovoltaic system in a Nigerian 33/11 kV distribution network

Frontiers in Energy Research
In this study, we investigate the impact of a 2.5 MW grid-connected solar photovoltaic generation (SPVG) plant installed at the Nigerian Defence Academy (NDA), Kaduna, on the 33/11 kV NDA distribution feeder network.
Nsikak Etim Asuquo, A. I. Araga, Dauda Dahiru, Kenneth E. Okedu, Kenneth E. Okedu, Ilhami Colak   +5 more
doaj   +1 more source

Oscillations of First Order Delay Dynamic Equations

, 2006
Stavroulakis, Ioannis/0000-0002-4810-0540Consider the first order linear delay dynamic equation of the forms x(Delta)(t) + p(t)x(tau(t)) = 0. (E) New oscillation criteria are established which contain well-known criteria for delay differential and ...
Sahiner, Y., Stavroulakis, I. P.
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source