Results 101 to 110 of about 5,677,110 (316)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The rapid growth of Waste Electrical and Electronic Equipment (WEEE) in the European Union highlights the need for a rigorous understanding of its long-term dynamics and the role of innovation in shaping its trajectory.
Cristian Busu +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Some Stability Results for Markovian Economic Semigroups [PDF]
The paper studies existence, uniqueness and stability of stationary equilibrium distributions in a class of stochastic dynamic models common to economic analysis.
Kevin Reffett +2 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Dynamic Stability and Reform of Political Institutions [PDF]
This paper studies dynamic, endogenous institutional change. We introduce the class of dynamic political games (DPGs), dynamic games in which future political aggregation rules are decided under current ones, and the resulting institutional choices do ...
Roger Lagunoff
core
Articulated heavy vehicles exhibit poor lateral stability, which may lead to unstable motion modes, e.g., trailer-sway and jackknifing, causing severe accidents.
Tarun Sharma, Yuping He
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Biomechanical differences between novice and experienced runners: a systematic review
BackgroundRunning offers substantial physical and psychological health benefits, however, novice runners experience a markedly higher incidence of running-related injuries than experienced runners.
Haisheng Shen +3 more
doaj +1 more source

