Results 161 to 170 of about 760,230 (317)

On the influence of sea state idealizations and wave directionality in dynamic stability assessments

open access: yes, 2013
Simplified spectral based methods, concluded feasible for on-board analysis of dynamic stability limits in previous studies, are here adjusted for use in short crested seas and applied on a RORO ship using detailed forecast 2D wave spectra and ...
Rosén, Anders   +3 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Gait variability and local dynamic stability are exacerbated by age and visual cues. [PDF]

open access: yesPeerJ
Moreno Jaramillo J   +4 more
europepmc   +1 more source

On the influence of sea state idealizations and wave directionality in dynamic stability assessments [Elektronisk resurs]

open access: yes, 2013
Simplified spectral based methods, concluded feasible for on-board analysis of dynamic stability limits in previous studies, are here adjusted for use in short crested seas and applied on a RORO ship using detailed forecast 2D wave spectra and ...
Palmquist, Mikael,   +3 more
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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