Results 81 to 90 of about 6,080,852 (309)
For sample return missions from deep space, a thin aeroshell capsule was proposed aimed at mitigating the aerodynamic heating during its reentry into the earth's atmosphere.
Hideto TAKASAWA +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Nash Equilibrium and Robust Stability in Dynamic Games: A Small-Gain Perspective [PDF]
This paper develops a novel methodology to study robust stability properties of Nash equilibrium points in dynamic games. Small-gain techniques in modern mathematical control theory are used for the first time to derive conditions guaranteeing uniqueness
Jiang, Zhong-Ping +2 more
core
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Causality in real-time dynamic substructure testing [PDF]
Causality, in the bond graph sense, is shown to provide a conceptual framework for the design of real-time dynamic substructure testing experiments. In particular, known stability problems with split-inertia substructured systems are reinterpreted as ...
Neild, S.A. +7 more
core +1 more source
Internal stability of reinforced retaining wall under earthquake loads
To analyze the internal stability of reinforced retaining wall under earthquake loads, according to the characteristics of layered filling, stratified compaction and horizontal layered arrangement of reinforcement strip, by selecting the logarithmic ...
JIA Liang 1, HE Shi-kai 1, LI Gang 2, GUO Jian 1, LIANG Rong 1
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Some Stability Results for Markovian Economic Semigroups [PDF]
The paper studies existence, uniqueness and stability of stationary equilibrium distributions in a class of stochastic dynamic models common to economic analysis.
Kevin Reffett +2 more
core
DYNAMIC STABILITY OF AN INITIALLY DEFLECTED RECTANGULAR PLATE UNDER AN INPLANE DYNAMIC MOMENT [PDF]
"In the following paper, the vibration of an initially deflected rectangular plate under a sinusoidally time-varying inplane moment is examined from the point of view of dynamic instability.
Konishi, Yasunori +3 more
core

