Results 31 to 40 of about 33,592 (217)

Dynamical properties of gene regulatory networks involved in long-term potentiation

Frontiers in Molecular Neuroscience, 2015
The long-lasting enhancement of synaptic effectiveness known as long-term potentiation (LTP) is considered to be the cellular basis of long-term memory. LTP elicits changes at the cellular and molecular level, including temporally specific alterations in
Gonzalo Sanchez Nido, Gonzalo Sanchez Nido, Margaret Mary Ryan, Margaret Mary Ryan, Lubica eBenuskova, Lubica eBenuskova, Joanna Margaret Williams, Joanna Margaret Williams   +7 more
doaj   +1 more source

Experimental studies of the influence of a gyroscopic damping system on the aeroelastic characteristics of a large aircraft model with elastic pylon-mounted engines under the wing

Научный вестник МГТУ ГА
During production of modern large transport aircraft, engine arrangement mounted on the elastic pylons under the wing is widely used. This arrangement of engines has certain advantages, however, there are also significant dynamic features due to the fact
Y. V. Petrov, M. V. Semakova, N. N. Medvedeva, V. G. Ugreninov   +3 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

The stability of paths in a dynamic network

Proceedings of the 2005 ACM conference on Emerging network experiment and technology - CoNEXT'05, 2005
Dynamic networks appear in several contexts: QoS routing faces the difficult problem of accurately and efficiently maintaining, distributing and updating network state information, and in wireless ad hoc networking, signal strength fluctuations complicate the choice of stable paths.
Kuipers, F.A. (author), Wang, H. (author), Van Mieghem, P. (author)   +2 more
openaire   +5 more sources

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Dynamic stability evaluation of submarine slopes with hydrate reservoir under influences of heat injection exploitation

Yantu gongcheng xuebao, 2022
The heat injection exploitation will destroy the temperature and pressure balance of hydrate reservoirs, cause hydrate dissociation, lead to the dramatic increase of pore pressure of strata, and then induce the instability of submarine slopes along the ...
NIAN Ting-kai , SONG Xiao-long , ZHANG Hao , RONG Ze
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Aerodynamic and stability analysis of the Safat01 aircraft [PDF]

Scientific Technical Review, 2015
This paper aimed to predict aerodynamic & stability data for the Safat01 aircraft. Because of its economic and time efficiency, the Digital DATCOM program has been used to predict the stability and control derivatives for the subsonic, low angle of ...
Qurashi Rania, Alhadi Mohmmed, Abudarag Sakher, Vujić Dragoljub   +3 more
doaj