Results 111 to 120 of about 5,677,110 (316)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Background: The 1 min sit-to-stand test (1-MSTST) is a widely used functional assessment involving repetitive sit-to-stand transitions. This study examined local dynamic stability during the 1-MSTST across three acceleration directions, compared young ...
Arunee Promsri +3 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Oscillations of First Order Delay Dynamic Equations
Stavroulakis, Ioannis/0000-0002-4810-0540Consider the first order linear delay dynamic equation of the forms x(Delta)(t) + p(t)x(tau(t)) = 0. (E) New oscillation criteria are established which contain well-known criteria for delay differential and ...
Sahiner, Y., Stavroulakis, I. P.
core
Solution of Time Fractional SIQR Epidemic System and Research with Respect to the Fractional Order
This article deals with the global existence and uniqueness of solutions to a fractional-order SIQR epidemic model, alongside its intricate chaotic and complex dynamics as functions of the fractional order.
Pingping Li, Zhen Wang, Gongsheng Li
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
En el presente trabajo se propone un procedimiento para estudiar la dinámica de lafrecuencia del sistema interconectado Ecuador-Colombia, ante la salida de unidadesgeneradoras cuando no se dispone de la información necesaria del sistema el ...
Marcelo Arias Castañeda +1 more
doaj
Stability in topological dynamics [PDF]
openaire +2 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

