Results 151 to 160 of about 4,021,919 (293)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Lumbar Dynamic Stabilization With 2-Stage Surgery: Early Results. [PDF]

Int J Spine Surg, 2022
Özer AF, Başak AT, Özbek MA, Hekimoğlu M, Aydın AL, Ateş Ö, Günerbüyük C, Akgül T, Sasani M, Öktenoğlu T.   +9 more
europepmc   +1 more source

Revealed preferences for macroeconomic stabilization [PDF]

In the new Keynesian model of endogenous stabilization governments have objectives with respect to macroeconomic performance, but are constrained by an augmented Phillips curve.
David Kiefer
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Biomechanical Effect of Hybrid Dynamic Stabilization Implant on the Segmental Motion and Intradiscal Pressure in Human Lumbar Spine. [PDF]

Bioengineering (Basel), 2022
Hsiao CK, Tsai YJ, Yen CY, Li YC, Hsiao HY, Tu YK.   +5 more
europepmc   +1 more source

Monetary and Fiscal Policy Design under EMU: A Dynamic Game Approach [PDF]

This paper analyzes the problem of designing macroeconomic stabilization policies within the European Monetary Union (EMU) as a dynamic game between a centralized monetary authority, the European Central Bank (ECB), and national fiscal policy makers. Non-
Joseph Plasmans, Jacob Engwerda, Bas van Aarle, Arie Weeren   +3 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Posterior Dynamic Stabilization with Limited Rediscectomy for Recurrent Lumbar Disc Herniation. [PDF]

Pain Res Manag, 2021
Luo L, Zhao C, Li P, Liu L, Zhou Q, Luo F, Liang L.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Partial triceps tendon transfer for dynamic stabilization in posterolateral rotatory instability of the elbow: a biomechanical study. [PDF]

Arch Orthop Trauma Surg
Pucher CJ, Lanzerath F, Kahmann SL, Hackl M, Müller LP, Leschinger T.   +5 more
europepmc   +1 more source