Results 71 to 80 of about 4,021,919 (293)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Scientific and Technical Center "Mining Equipment". Scientific Support of Production

open access: yesМеханика машин, механизмов и материалов, 2012
The article shows the relationship of science and industry, disclosing the results of the most important joint research, correcting the technical policy of the enterprise.
P.L. Mariev   +3 more
doaj  

Dynamic robust stabilization of stochastic differential control systems [PDF]

open access: yes, 2013
The stabilization of stochastic differential control systems by means of dynamic feedback laws is provided. We extend the well-known Artstein–Sontag theorem to derive the necessary and sufficient conditions for the dynamic robust stabilization of ...
Abedi, Fakhreddin, Leong, Wah June
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Dynamic stabilization of filamentation instability

open access: yes, 2018
The paper presents a study on dynamic stabilization of filamentation instability driven by an electron beam introduced into a plasma. The results presented in the paper demonstrate that the filamentation instability is successfully stabilized by the ...
487728   +40 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Dynamic Neuromuscular Stabilization (DNS)

open access: yesResearch in Sport Education and Sciences, 2022
Elif Aybüke YILMAZ
doaj   +1 more source

Optimical Commodity Price Stabilizador Over the Business Cycle [PDF]

open access: yes
This paper develops a model to study the design, characterization and dynamic implications of stabilization policies in a dynamic general equilibrium model of the business cycle for an economy tainted by the Dutch disease.
Rodrigo Suescún M.
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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