Results 91 to 100 of about 612,889 (331)

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu   +15 more
wiley   +1 more source

An Approach to Validating theAccessibility of Dynamic Web Pages [PDF]

open access: gold, 2023
Hristo Hristov   +3 more
openalex   +1 more source

Technical development of PubMed Interact: an improved interface for MEDLINE/PubMed searches

open access: yesBMC Medical Informatics and Decision Making, 2006
Background The project aims to create an alternative search interface for MEDLINE/PubMed that may provide assistance to the novice user and added convenience to the advanced user.
Fontelo Paul, Muin Michael
doaj   +1 more source

Toward a Species Search Engine: KISSE Offers a Rigorous Statistical Framework for Bone Collagen Tandem Mass Spectrometry Data

open access: yesAdvanced Science, EarlyView.
The Species Search Engine (KISSE) is a novel statistical approach for identifying species from collagen peptides, using a curated library of sequences and their relative abundances derived from shotgun proteomics. Abstract DNA and bone collagen are two key sources of resilient molecular markers used to identify species from their remains.
Hassan Gharibi   +8 more
wiley   +1 more source

How People Re-find Information When the Web Changes [PDF]

open access: yes, 2004
This paper investigates how people return to information in a dynamic information environment. For example, a person might want to return to Web content via a link encountered earlier on a Web page, only to learn that the link has since been removed ...
Teevan, Jaime
core   +1 more source

Choose Your Own Research Data Management Guidance

open access: yesInternational Journal of Digital Curation, 2017
The GW4 Research Data Services Group has developed a Research   Data Management Triage Tool to help researchers find answers quickly  to the more common research data queries, and direct them to appropriate guidance and sources of advice for more complex
Alex Ball   +3 more
doaj   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

open access: yesAdvanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu   +13 more
wiley   +1 more source

Single‐Cell Transcriptome Profiling Reveals Conserved IFNγ‐IL8 Signaling‐Induced Antibacterial Neutrophil States during Bacterial Infection

open access: yesAdvanced Science, EarlyView.
SummaryThis study constructs a single‐cell immune atlas of Nile tilapia across multiple time points during Streptococcus agalactiae infection, revealing dynamic immune cell responses and subtype transitions. It identifies a conserved IFNr‐STAT1‐IL8 axis driving il8+ neutrophils activation and antibacterial function, supported by cross‐species ...
Xue Zhai   +14 more
wiley   +1 more source

The ICAP (Interactive Course Assignment Pages) Publishing System

open access: yesCode4Lib Journal, 2008
The ICAP publishing system is an open source custom content management system that enables librarians to easily and quickly create and manage library help pages for course assignments (ICAPs), without requiring knowledge of HTML or other web technologies.
Kim Griggs, Margaret Mellinger
doaj  

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