Results 101 to 110 of about 612,889 (331)
Personalised Medical Reference to General Practice Notebook (GPnotebook) - an evolutionary tale
In 1992, a group of medical students and a UK general practitioner were awarded the John Perry Prize for an MS-DOS-based flexible, dynamic, updateable and structured computerised medical reference system.
James McMorran, Damian Crowther
doaj +1 more source
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng+40 more
wiley +1 more source
Dynamic web page authoring by example using ontology-based domain knowledge [PDF]
José A. Macías, Pablo Castells
openalex +2 more sources
Digital libraries and World Wide Web sites and page persistence.
Web pages and Web sites, some argue, can either be collected as elements of digital or hybrid libraries, or, as others would have it, the WWW is itself a library. We begin with the assumption that Web pages and Web sites can be collected and categorized.
Wallace Koehler
doaj
This study identified that STK33 may serve as a target of Bufalin, which induces the degradation of STK33 and inhibits the growth of TNBC. Furthermore, STK33 is highly expressed in TNBC and enhances TNBC cell proliferation by phosphorylating and stabilizing CCAR1.
Shilong Jiang+11 more
wiley +1 more source
Integrating web services into data intensive web sites [PDF]
Designing web sites is a complex task. Ad-hoc rapid prototyping easily leads to unsatisfactory results, e.g. poor maintainability and extensibility.
Domingue, John+2 more
core
Microcapsule‐based intelligent coatings (MICs) have shown great potential in the fields of biomedicine, smart buildings, marine protection, and aerospace. However, they currently face challenges in the integration of coating functions and applications in complex systems.
Yue Zhao+5 more
wiley +1 more source
This study demonstrates that Akkermansia muciniphila alleviates colitis by enhancing intestinal α1,2‐fucosylation through its metabolite N‐acetylspermidine. Mechanistically, N‐acetylspermidine‐induced PIM1 inhibition promotes HDAC2‐mediated reduction of chromatin accessibility at TP73, thereby upregulating C1GALT1C1 to boost α1,2‐fucosylation.
Ye Yao+10 more
wiley +1 more source
ONLINE VS TRADITIONAL; MARKETING CHALLENGE IN THE TELECOM MARKET IN BOSNIA AND HERZEGOVINA
Understanding consumer behavior in media advertising enables companies to effectively direct marketing activities toward the target market. Today, companies are expected to continually communicate with current and potential customers.
Tarik Zaimović, Adnan Suturović
doaj +2 more sources
A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao+12 more
wiley +1 more source