Results 101 to 110 of about 625,358 (332)

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Dynamic web page authoring by example using ontology-based domain knowledge [PDF]

, 2003
José A. Macías, Pablo Castells
openalex   +2 more sources

The ICAP (Interactive Course Assignment Pages) Publishing System

Code4Lib Journal, 2008
The ICAP publishing system is an open source custom content management system that enables librarians to easily and quickly create and manage library help pages for course assignments (ICAPs), without requiring knowledge of HTML or other web technologies.
Kim Griggs, Margaret Mellinger
doaj  

Personalised Medical Reference to General Practice Notebook (GPnotebook) - an evolutionary tale

Journal of Innovation in Health Informatics, 2002
In 1992, a group of medical students and a UK general practitioner were awarded the John Perry Prize for an MS-DOS-based flexible, dynamic, updateable and structured computerised medical reference system.
James McMorran, Damian Crowther
doaj   +1 more source

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

Advanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang, Yunda Fang, Yuheng Lian, Ziyang Kong, Jia Miao, Yanqi Chen, Wen Li, Feiyan Chen, Bin Zhang, Yao Chen, Yaoyao Bian   +10 more
wiley   +1 more source

Best‐Practice Reporting for Porous Materials Adsorption Data

Angewandte Chemie, EarlyView.
Digital reporting of adsorption data critically relies on standardization enabling FAIR data management, AI‐based discovery, and massive data mining for the exploration of advanced porous materials in sustainable processing for future society. Abstract Recent decades have seen an enormous evolution of novel porous materials for catalysis, energy ...
Daniel W. Siderius, Jack D. Evans, Paul Iacomi, Louis Vanduyfhuys, Veronique Van Speybroeck, Volodymyr Bon, Stefan Kaskel   +6 more
wiley   +2 more sources

Integrating web services into data intensive web sites [PDF]

, 2004
Designing web sites is a complex task. Ad-hoc rapid prototyping easily leads to unsatisfactory results, e.g. poor maintainability and extensibility.
Domingue, John, Lei, Yuangui, Motta, Enrico   +2 more
core  

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

Advanced Science, EarlyView.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu, Yuxin Qiu, Guzhong Chen, Wenyao Chen, Xiang Zhang, Zhiwen Qi, Xuezhi Duan, De Chen, Zhen Song   +8 more
wiley   +1 more source

Three‐Segment Protein Labeling Using a Highly Efficient and Cysteine‐Less Split Intein Identified with Computational Prediction of Aggregation Properties

Angewandte Chemie, EarlyView.
Tandem protein trans‐splicing (PTS) assembles a protein from three segments. Expanding this technology to individually treat cysteines in each segment, for example, for chemical labeling using thiol bioconjugation, the authors identify a second, highly efficient cysteine‐less split intein.
Christoph Humberg, Jonas Kröger, Shmuel Pietrokovski, Henning D. Mootz   +3 more
wiley   +2 more sources

Digital libraries and World Wide Web sites and page persistence.

Information Research: An International Electronic Journal, 1999
Web pages and Web sites, some argue, can either be collected as elements of digital or hybrid libraries, or, as others would have it, the WWW is itself a library. We begin with the assumption that Web pages and Web sites can be collected and categorized.
Wallace Koehler
doaj