Results 121 to 130 of about 612,889 (331)

RAId_DbS: mass-spectrometry based peptide identification web server with knowledge integration

open access: yesBMC Genomics, 2008
Background Existing scientific literature is a rich source of biological information such as disease markers. Integration of this information with data analysis may help researchers to identify possible controversies and to form useful hypotheses for ...
Ogurtsov Aleksey Y   +2 more
doaj   +1 more source

A Charge‐Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
DNA gel bandage (DNAgb) is designed to precisely target the site of inflammation of IBD, by achieving dual specific localization of inflamed mucosa through electrostatic interactions and ApITGA4‐mediated affinity targeting. DNAgb effectively the activation of inflammatory pathways and reshapes the immune microenvironment.
Peifen Lu   +9 more
wiley   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian   +7 more
wiley   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang   +15 more
wiley   +1 more source

DNA‐Based Hydrogels for Musculoskeletal Reconstruction: Harnessing Dynamic Programmability and Multimodal Therapeutic Integration

open access: yesAdvanced Science, EarlyView.
DNA‐based hydrogels serve dual roles as structural scaffolds and therapeutic platforms, offering innovative solutions for musculoskeletal regeneration with multifunctional abilities. Abstract Musculoskeletal disorders, including bone fractures, osteoarthritis, and muscle injuries, represent a leading cause of global disability, revealing the urgency ...
Ruijianghan Shi   +4 more
wiley   +1 more source

Aqueous Zinc‐Based Batteries: Active Materials, Device Design, and Future Perspectives

open access: yesAdvanced Energy Materials, EarlyView.
This review conducts a comprehensive analysis of aqueous zinc‐based batteries (AZBs) based on their intrinsic mechanisms, including redox reactions, ion intercalation reactions, alloying reactions, electrochemical double‐layer reactions, and mixed mechanisms, systematically discussing recent advancements in each type of AZBs.
Yan Ran, Fang Dong, Shuhui Sun, Yong Lei
wiley   +1 more source

Impacts of geopolitics and policy on Latin American biodiversity and water resources

open access: yesAgribusiness, EarlyView.
Abstract Latin America is a major agricultural producer with important natural resources. Efforts have been made to protect sensitive areas but are hindered by agricultural trade disruptions outside the control of individual countries due to globally integrated crop markets.
Jerome Dumortier   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy