Results 81 to 90 of about 644,969 (331)

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

open access: yesAdvanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun   +12 more
wiley   +1 more source

Resolution of static clones in dynamic Web pages [PDF]

open access: yesFifth IEEE International Workshop on Web Site Evolution, 2003. Theme: Architecture. Proceedings., 2004
Cloning is extremely likely to occur in Web sites, much more so than in other software. While some clones exist for valid reasons, or are too small to eliminate, cloning percentages of 30% or higher-not uncommon in Web sites-suggest that some improvements can be made.
Nikita. Synytskyy, J.R. Cordy, T. Dean
openaire   +1 more source

Enhancing the Ultrasonic Welding of Wood Using 3D Printed Lignin Energy Directors

open access: yesAdvanced Science, EarlyView.
Sustainable manufacturing for lightweight structures using ecofriendly materials will be key to reducing material consumption and lowering carbon footprints. Here, an approach is presented to weld wood using ultrasonic vibrations with material at the joint interface to direct energy.
Muhamad Amani   +6 more
wiley   +1 more source

Planning-based Approach for Optimizing the Display of Online Advertising Campaigns [PDF]

open access: yes, 2010
In a realistic context, the online advertisements have constraints such as a certain number of clicks to draw, as well as a lifetime. Furthermore, receiving a click is usually a very rare event.
Girgin, Sertan   +3 more
core   +1 more source

A Descriptive Model of Robot Team and the Dynamic Evolution of Robot Team Cooperation

open access: yes, 2005
At present, the research on robot team cooperation is still in qualitative analysis phase and lacks the description model that can quantitatively describe the dynamical evolution of team cooperative relationships with constantly changeable task demand in
Cheng, Xian-yi   +4 more
core   +2 more sources

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

open access: yesAdvanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen   +11 more
wiley   +1 more source

Choose Your Own Research Data Management Guidance

open access: yesInternational Journal of Digital Curation, 2017
The GW4 Research Data Services Group has developed a Research   Data Management Triage Tool to help researchers find answers quickly  to the more common research data queries, and direct them to appropriate guidance and sources of advice for more complex
Alex Ball   +3 more
doaj   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
ABSTRACT The cytosine (C) modifications 5‐methylcytosine (mC) and 5‐hydroxymethylcytosine (hmC) are central regulatory elements of mammalian genomes. Both marks occur in double‐stranded DNA in either strand‐symmetric or ‐asymmetric fashion, but it is still poorly understood how this symmetry information is selectively read out by the nuclear proteome ...
Lena Engelhard   +8 more
wiley   +1 more source

Enhancing the Ranking of a Web Page in the Ocean of Data [PDF]

open access: yesDatabase Systems Journal, 2013
In today's world, web is considered as ocean of data and information (like text, videos, multimedia etc.) consisting of millions and millions of web pages in which web pages are linked with each other like a tree.
Hitesh KUMAR SHARMA
doaj  

Pricing Policies for Selling Indivisible Storable Goods to Strategic Consumers

open access: yes, 2018
We study the dynamic pricing problem faced by a monopolistic retailer who sells a storable product to forward-looking consumers. In this framework, the two major pricing policies (or mechanisms) studied in the literature are the preannounced (commitment)
Berbeglia, Gerardo   +2 more
core   +1 more source

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