Results 91 to 100 of about 4,088,927 (359)

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Dynamical and statistical downscaling of a global seasonal hindcast in eastern Africa

Climate Services, 2018
Within the FP7 EUPORIAS project we have assessed the utility of dynamical and statistical downscaling to provide seasonal forecast for impact modelling in eastern Africa.
Grigory Nikulin, Shakeel Asharaf, María Eugenia Magariño, Sandro Calmanti, Rita M. Cardoso, Jonas Bhend, Jesús Fernández, María Dolores Frías, Kristina Fröhlich, Barbara Früh, Sixto Herrera García, Rodrigo Manzanas, José Manuel Gutiérrez, Ulf Hansson, Michael Kolax, Mark A. Liniger, Pedro M.M. Soares, Christoph Spirig, Ricardo Tome, Klaus Wyser   +19 more
doaj   +1 more source

An Enhanced Archive Facilitating Climate Impacts and Adaptation Analysis [PDF]

, 2014
We describe the expansion of a publicly available archive of downscaled climate and hydrology projections for the United States. Those studying or planning to adapt to future climate impacts demand downscaled climate model output for local or regional ...
Arnold, James W., Brekke, Levi, Cayan, Daniel R., Dettinger, Michael D., Duffy, Philip B., Long, J., Maurer, Edwin P., Pruitt, Tom, Thrasher, Bridget   +8 more
core   +1 more source

Small and Simple Molecular Structure Based Thermally Stable Ruthenium Precursor in Advancing Ruthenium ALD Process for Scaled Interconnect Metallization

Advanced Science, EarlyView.
A thermally robust (≈400 °C), critically small‐size‐simple ligand structure ruthenium (Ru) precursor enables exceptional growth per cycle (≈1.28 Å cycle−1), short incubation (≈8 cycles), ultralow resistivity (8.65 µΩ cm) and outstanding substrate selectivity via atomic layer deposition (ALD) process at high temperatures, overcoming prior Ru‐ALD ...
Hideaki Nakatsubo, Debananda Mohapatra, Eun‐Soo Lee, Jeongha Kim, Iaan Cho, Masato Iseki, Toshiyuki Shigetomi, Ryosuke Harada, Sang‐Woong Na, Taehoon Cheon, Bonggeun Shong, Soo‐Hyun Kim   +11 more
wiley   +1 more source

Representing climate and extreme weather events in integrated assessment models: A review of existing methods and options for development [PDF]

, 2003
The lack of information about future changes in extreme weather is a major constraint of Integrated Assessment Models (IAMs) of climate change. The generation of descriptions of future climate in current IAMs is assessed.We also review recent work on ...
Goodess, CG, Hanson, C, Hulme, M, Osborn, TJ   +3 more
core   +1 more source

Analysis of Multiscale Condensation Phenomena Using a Zero‐Shot Computer Vision Framework

Advanced Science, EarlyView.
A zero‐shot computer vision framework quantifies multiscale condensation dynamics by automatically segmenting droplets and extracting physical parameters without labeled data. The workflow integrates data mining and statistical analysis to reveal droplet growth, coalescence statistics, and sweeping behaviors, enabling label‐free measurement of heat ...
Donghyeong Lee, Seokwan Roh, Jaewoo Jeong, Kuk‐Jin Yoon, Jungchul Lee, Youngsuk Nam   +5 more
wiley   +1 more source

Future Changes in Regional Tropical Cyclone Wind, Precipitation, and Flooding Using Event‐Based Downscaling

Earth's Future
Understanding changes in the hazard component of climate risk is important to inform societal resilience planning in a changing climate. Here, we examine local changes in wind speed, rainfall, and flooding related to tropical cyclones (TCs) and compare ...
Alexander Michalek, James M. Done, Gabriele Villarini   +2 more
doaj   +1 more source

Practical rare event sampling for extreme mesoscale weather

, 2019
Extreme mesoscale weather, including tropical cyclones, squall lines, and floods, can be enormously damaging and yet challenging to simulate; hence, there is a pressing need for more efficient simulation strategies.
Abbot, Dorian S., O'Neill, Morgan E, Plotkin, David A., Weare, Jonathan, Webber, Robert J.   +4 more
core   +1 more source

Uncertainty in projections of streamflow changes due to climate change in California [PDF]

, 2005
Understanding the uncertainty in the projected impacts of climate change on hydrology will help decision-makers interpret the confidence in different projected future hydrologic impacts.
Duffy, Philip B., Maurer, Edwin P.
core   +2 more sources