Results 191 to 200 of about 58,720 (307)

Bayesian Dynamical Modeling of Fixational Eye Movements. [PDF]

Biol Cybern
Schwetlick L, Reich S, Engbert R.
europepmc   +1 more source

Dynamical modeling of pro- and anti-inflammatory cytokines in the early stage of septic shock. [PDF]

In Silico Biol, 2020
Tallon J, Browning B, Couenne F, Bordes C, Venet F, Nony P, Gueyffier F, Moucadel V, Monneret G, Tayakout-Fayolle M.   +9 more
europepmc   +1 more source

Dynamic causal modeling

Scholarpedia, 2010
André C. Marreiros, Klaas E. Stephan, Karl J. Friston   +2 more
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Inter-subject and inter-parcellation variability of resting-state whole-brain dynamical modeling.

Neuroimage, 2021
Popovych OV, Jung K, Manos T, Diaz-Pier S, Hoffstaedter F, Schreiber J, Yeo BTT, Eickhoff SB.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Development and application of a novel tumor habitat analysis technique based on dynamical modeling. [PDF]

Med Phys
Stevens JB, Je J, Riley BA, Mowery YM, Brizel DM, Liu JG, Wang C, Lafata KJ.   +7 more
europepmc   +1 more source

Dynamical modeling predicts an inflammation-inducible CXCR7+ B cell precursor with potential implications in lymphoid blockage pathologies. [PDF]

PeerJ, 2020
Enciso J, Mendoza L, Álvarez-Buylla ER, Pelayo R.   +3 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Allosteric communication in molecular machines via information exchange: what can be learned from dynamical modeling. [PDF]

Biophys Rev, 2020
Loutchko D, Flechsig H.
europepmc   +1 more source