Results 161 to 170 of about 225,954 (249)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

J0540203 Dynamic Characteristic Analysis of Floating Offshore Wind Turbine-Generator System : Correlation Analysis of Power Output Fluctuation and Floating Platform Motion

, 2014
Tetsuya WAKUI, Motoki Yoshimura, Ryohei Yokoyama   +2 more
openalex   +2 more sources

A direct look at RNAi screens

Molecular Systems Biology, 2012
Alexis R Barr, Chris Bakal
doaj   +1 more source

Self-organizing neuromorphic nanowire networks as stochastic dynamical systems. [PDF]

Nat Commun
Milano G, Michieletti F, Pilati D, Ricciardi C, Miranda E.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Substitutions, tiling dynamical systems and minimal self-joinings

, 2014
Y. G. Son
openalex   +2 more sources

Statistical energy conservation principle for inhomogeneous turbulent dynamical systems [PDF]

, 2015
Andrew J. Majda
openalex   +1 more source

Time-lagged recurrence: A data-driven method to estimate the predictability of dynamical systems. [PDF]

Proc Natl Acad Sci U S A
Dong C, Faranda D, Gualandi A, Lucarini V, Mengaldo G.   +4 more
europepmc   +1 more source

On the potential of transfer entropy in turbulent dynamical systems. [PDF]

Sci Rep, 2023
Massaro D, Rezaeiravesh S, Schlatter P.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source