Re-engineering the disordered mind: clinical experimentation, dynamical systems, and AI for personalized psychiatry. [PDF]
Kheirkhah M +7 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Neuromorphic robust framework for integrated estimation and control in dynamical systems using spiking neural networks. [PDF]
Ahmadvand R, Sharif SS, Banad YM.
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Unveiling the immoral ramp feature of dissolved oxygen signals with dynamical systems analysis: perspectives for robust soft-sensor development. [PDF]
Schneider MY, Torfs E, Carbajal JP.
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Dynamical systems theory as an organizing principle for single-cell biology. [PDF]
Islam S, Bhattacharya S.
europepmc +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Temporal dynamics of neural activity in autism: dynamical systems perspective on sensitivity, neural learning, and social interactions. [PDF]
Malaia EA, Ahn S, Rubchinsky LL.
europepmc +1 more source

