Results 21 to 30 of about 33,514 (190)

Berry Phases on Virasoro Orbits

, 2017
We point out that unitary representations of the Virasoro algebra contain Berry phases obtained by acting on a primary state with conformal transformations that trace a closed path on a Virasoro coadjoint orbit.
Oblak, Blagoje
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Synchronization versus stability of the invariant distribution for a class of globally coupled maps

, 2018
We study a class of globally coupled maps in the continuum limit, where the individual maps are expanding maps of the circle. The circle maps in question are such that the uncoupled system admits a unique absolutely continuous invariant measure (acim ...
Bálint, Péter, Keller, Gerhard, Sélley, Fanni M., Tóth, Imre Péter   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Conformal mapping methods for interfacial dynamics

, 2004
The article provides a pedagogical review aimed at graduate students in materials science, physics, and applied mathematics, focusing on recent developments in the subject.
A. Levermann, B. Bensimon, B. D. H.G.E. Hentschel, D. Crowdy, D. Crowdy, D. Crowdy, D. Crowdy, D.G. Crowdy, E. Somfai, E. Somfai, F. Barra, F. Barra, F. Parisio, G. Carrier, H. Shapiro, J.W. Maclean, K. Kornev, L. Niemeyer, L.M. Cummings, L.P. Kadanoff, M. Amar Ben, M. Kruskal, M.B. Hastings, M.B. Hastings, M.B. Hastings, M.G. Stepanov, M.H. Jensen, M.Z. Bazant, M.Z. Bazant, N. Muskhelishvili, P. Saffman, P.G. Saffman, P.L. Duren, R. Hopper, R.C. Ball, R.V. Churchill, S. Howison, S. Richardson, S. Richardson, S. Richardson, S. Richardson, S. Tanveer, S. Tanveer, S. Tanveer, S.D. Howison, T. Needham, T. Yoshikawa, T.A. Witten, T.C. Halsey, V.E. Zakharov, W. Kager, W. Wang, W. Wang, W.-S. Dai   +53 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Simultaneous Border-Collision and Period-Doubling Bifurcations

, 2009
We unfold the codimension-two simultaneous occurrence of a border-collision bifurcation and a period-doubling bifurcation for a general piecewise-smooth, continuous map.
Angulo F., Berberian S. K., D. J. W. Simpson, di Bernardo M., Guckenheimer J., J. D. Meiss, Kolman B., Robinson R. C.   +7 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source