Results 131 to 140 of about 9,416,898 (346)
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Discrete Dynamics in Nature and Society
doaj +1 more source
Moving Targets: Aggressiveness, Attainment, and Temporal Dynamics in Corporate Carbon Targets
Patrick J. Callery, Eun‐Hee Kim
openalex +1 more source
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles [PDF]
Paul S. Maddox +4 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Discrete Dynamics in Nature and Society
doaj +1 more source
On the dynamics of closed-loop supply chains under remanufacturing lead time variability
Roberto Domínguez +3 more
openalex +2 more sources
Active DNA unwinding dynamics during processive DNA replication [PDF]
José A. Morín +7 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

