Results 171 to 180 of about 5,067,506 (313)

Retracted: How Does Fiscal Policy Affect Bank Credit? Evidence from China

open access: yesDiscrete Dynamics in Nature and Society
Discrete Dynamics in Nature and Society
doaj   +1 more source

Retracted: Construction of Credibility Model for Evaluating the Effectiveness of Ecological Civilization Education

open access: yesDiscrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Integrative modeling of the genome structure and dynamics in fission yeast. [PDF]

open access: yesProc Natl Acad Sci U S A
Shinkai S   +9 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Retracted: Construction and Empirical Study of Learner Portrait in Online General Education Course

open access: yesDiscrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source

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