Results 21 to 30 of about 9,416,898 (346)

Dynamic DNA Underpins Chromosome Dynamics [PDF]

open access: yesBiophysical Journal, 2013
A recent article by Meyer and co-workers provides a detailed description of the dynamics of base-step conformational transitions and of the first steps to the basepair opening. These results underpin the essential role that DNA dynamics place in the DNA structural transitions that accompany the active processes of transcription, replication, and ...
openaire   +2 more sources

Heterochromatin Dynamics

open access: yesPLoS Biology, 2003
Heterochromatin is usually thought of as a stable and inactive region of the genome.
openaire   +5 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus   +6 more
wiley   +1 more source

Molecular Dynamics Simulations [PDF]

open access: yes, 2003
A tutorial introduction to the technique of Molecular Dynamics (MD) is given, and some characteristic examples of applications are described. The purpose and scope of these simulations and the relation to other simulation methods is discussed, and the ...
Alder B J   +59 more
core   +2 more sources

From molecular dynamics to Brownian dynamics [PDF]

open access: yesProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2014
Three coarse-grained molecular dynamics (MD) models are investigated with the aim of developing and analysing multi-scale methods which use MD simulations in parts of the computational domain and (less detailed) Brownian dynamics (BD) simulations in the remainder of the domain. The first MD model is formulated in one spatial dimension.
openaire   +4 more sources

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt   +2 more
wiley   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Human Center of Gravity Dynamics a New Parameter of Motor Development Functions [PDF]

open access: yes, 2001
A study of a new parameter of human growth and development was conducted. The percentage of the height of body gravity center to the stature in supine position was measured in males and females during the period of pre-puberty (l995), young and adult ...
Sofwanhadi, R. (Rio)
core  

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Curvaton Dynamics

open access: yes, 2003
In contrast to the inflaton's case, the curvature perturbations due to the curvaton field depend strongly on the evolution of the curvaton before its decay. We study in detail the dynamics of the curvaton evolution during and after inflation. We consider
de Austri, Roberto Ruiz   +3 more
core   +1 more source

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