Results 51 to 60 of about 115,478 (306)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Journal of Education, Humanities and Social SciencesThis research focuses on the attempts of individuals at different social levels within Chinese and Western cultural backgrounds to communicate and collaborate harmoniously.
Haochen Zhang
semanticscholar +1 more source
ULAMA DAN PESANTREN DALAM DINAMIKA POLITIK DAN KULTUR NAHDLATUL ULAMA
Ulul Albab, 2013 The article endeavors to trace power relationship between muslim religious leaders (ulama) and islamic boarding school (pesantren) in the political dynamics of Nahdlatul Ulama (NU).
Wasisto Raharjo Jati
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Niestabilność konstytucyjna jako instrument stabilizacji rządu. Przypadek Kirgistanu
Świat Idei i Polityki, 2007 The article analyses the issues connected with the creation and functioning of the constitution in post-communist Kyrgyzstan. Ostentatious law and order, repeatedly declared devotion to the principle of 'superiority of the constitution' and ritual ...
Nartsiss Shukuralieva
doaj +1 more source
How Provisional Improvement Notices Influence Employee Voice and Silence
Safety, 2023 Health and safety representatives (HSR) have the power to issue provisional improvement notices (PIN) to their employer for safety breaches. This paper examines how PINs influence workplace dynamics or employee voice.
Phillip Ho
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source