Results 121 to 130 of about 1,102,790 (312)

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

open access: yesAdvanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen   +16 more
wiley   +1 more source

Gender Construction, Stereotype, and Power Dynamics in Stromae’s Tous Les Mêmes: Critical Discourse Analysis

open access: yesRainbow: Journal of Literature, Linguistics and Culture
Tous Les Mêmes is a popular song in the album Racine Carrée by Stromae, listened all around Belgium and France. The song was written in French and showed a complex unhealthy relationship within a man and a woman.
Aurelia Rizky Ediana
doaj   +1 more source

Aging, Gender and Neighbourhood Determinants of Distance Traveled: A Multilevel Analysis in the Hamilton CMA [PDF]

open access: yes
The objective of this study is to investigate the determinants of mean trip distance traveled by different mode types. The study uses data from the Hamilton CMA in Canada, and multilevel models to investigate demographic aging factors, gender ...
Antonio P�ez, Ruben Mercado
core  

SMEs in Focus : Exploring the experience of micro, small and medium enterprise owners in Malta [PDF]

open access: yes, 2013
Report commissioned by the Ministry for Fair Competition, Small Business and Consumers in 2011. In-depth qualitative interviews were carried out on a purposive sample of business owners (n=31) to explore the relational dynamics at the root of doing ...
Martin, Gillian M.
core  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Gender and Cooperation in Children: Experiments in Colombia and Sweden [PDF]

open access: yes
This paper compares cooperation among Columbian and Swedish children aged 9-12. We illustrate the dynamics of the prisoner’s dilemma in a new task that is easily understood by children and performed during a physical education class.
Cárdenas, Juan-Camilo   +3 more
core  

A Wearable Brain–Computer Interface for Mitigating Car Sickness via Attention Shifting

open access: yesAdvanced Science, EarlyView.
Car sickness poses a major challenge in vehicular travel, yet effective nonpharmacological solutions are scarce. We developed a wearable, closed‐loop mindfulness BCI that uses real‐time EEG‐based neurofeedback to shift attention away from motion‐induced discomfort. Validated in real‐car experiments involving >100$>100$ susceptible individuals, over 83%
Jiawei Zhu   +14 more
wiley   +1 more source

GET SUBJECT SPORT -The Games We Used to Play An Application of Survival Analysis to the Sporting Life-course. ESRI WP272. January 2009 [PDF]

open access: yes, 2009
In the absence of longitudinal data, recall data is used to examine participation in sport. Techniques of survival analysis are adapted and applied to illuminate the dynamics of sporting life. The likelihood of participation has a distinct pattern across
Lunn, Pete
core  

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

Fashioning identities : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Sociology at Massey University [PDF]

open access: yes, 1993
This research addresses the way in which individual and collective identities are constructed through fashions in the contemporary western world. The reciprocal and interdependent relationship of processually emergent identities, and fashion as a ...
Green, Nicola Catherine
core  

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