Results 131 to 140 of about 1,102,790 (312)

Paving the Way to Elucidate Hg's Role in Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li   +10 more
wiley   +1 more source

Modern condition of labor migration from Ukraine to the EU and the prospects for its regulation [PDF]

open access: yes, 2017
The analysis of state and development dynamics of labour migration from Ukraine to the EU made in the context of: gender, age, level of education, country of destination, sector of employment and so on.
Adamets, Tetiana, Illiashenko, Sergii
core  

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

Who gets the Carrot and Who gets the Stick? Evidence of Gender Disparities in Executive Remuneration [PDF]

open access: yes
This paper offers a new explanation of the gender pay gap in leadership positions by examining the relationship between managerial bonuses and company performance.
Haslam, S.A.   +4 more
core   +1 more source

Missing Women and Bare Branches: Gender Balance and Conflict [PDF]

open access: yes, 2005
The emerging subfield of “security demographics” examines the linkages between population dynamics and the security trajectories of nation-states.
den Boer, Andrea, Hudson, Valerie M
core  

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

open access: yesAdvanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui   +9 more
wiley   +1 more source

To the question about the dynamics of changes of gender identity

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2018
The article offers a theoretical and empirical justification for the latent process of changes in gender identity. As the object of research, the phenomenon of performative character of gender identity is considered as a property that allows to design ...
Maria N. Rothstein
doaj  

Gender and antimicrobial resistance: a conceptual framework for researchers working in livestock systems

open access: yesFrontiers in Veterinary Science
BackgroundTo promote gender mainstreaming in future AMR research projects and policy implementation within livestock and other systems, researchers need to embrace gender-responsive research methodologies.
Fiona Emdin   +4 more
doaj   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

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