Results 1 to 10 of about 72,840 (299)
Objectives Disease-specific, well-defined and validated clinical outcome measures are essential in designing research studies. Poorly defined outcome measures hamper pooling of data and comparisons between studies.
Florian Gahleitner +13 more
doaj +1 more source
Could New Generations of Sensors Reshape the Management of Parkinson’s Disease?
Parkinson's disease (PD) is a chronic neurologic disease that has a great impact on the patient’s quality of life. The natural course of the disease is characterized by an insidious onset of symptoms, such as rest tremor, shuffling gait, bradykinesia ...
Oleg S. Levin +3 more
doaj +1 more source
Proceedings of the 4th BEAT-PCD Conference and 5th PCD Training School
Primary ciliary dyskinesia (PCD) is an inherited ciliopathy leading to chronic suppurative lung disease, chronic rhinosinusitis, middle ear disease, sub-fertility and situs abnormalities.
Laura E. Gardner +24 more
doaj +1 more source
Tardive Dyskinesia and Treatment Approaches [PDF]
Tardive dyskinesia is an iatrogenic movement disorder with an incompletely determined etiology. Involuntary movements can effect oral, lingual, facial, corporal muscles and can be permanent. Tardive dyskinesia is one of the most important side effects of
Mehmet Emin Demirkol +3 more
doaj +1 more source
After long-term use of levodopa, Parkinson's patients almost inevitably develop dyskinesia, a kind of drug side effect manifesting as uncontrollable choreic movements and dystonia, which could be crippling yet have limited therapeutic options ...
Yi Wu +9 more
doaj +1 more source
General anesthesia is usually selected when patients cannot remain still during surgery with local anesthesia. However, damage to the lungs from positive pressure ventilation under general anesthesia is a major concern in patients with Parkinson’s ...
Takafumi Suzuki +5 more
doaj +1 more source
Striatal D1 Dopamine Neuronal Population Dynamics in a Rat Model of Levodopa-Induced Dyskinesia
BackgroundThe pathophysiology of levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD) is not well understood. Experimental data from numerous investigations support the idea that aberrant activity of D1 dopamine receptor-positive medium spiny ...
Shasha Gao +8 more
doaj +1 more source
Clinical care for primary ciliary dyskinesia: current challenges and future directions
Primary ciliary dyskinesia (PCD) is a rare genetic disease that affects the motility of cilia, leading to impaired mucociliary clearance. It is estimated that the vast majority of patients with PCD have not been diagnosed as such, providing a major ...
Bruna Rubbo, Jane S. Lucas
doaj +1 more source
Background: Adaptive Deep Brain Stimulation (aDBS) is now considered as a new feasible and effective paradigm to deliver DBS to patients with Parkinson's disease (PD) in such a way that not only stimulation is personalized and finely tuned to the ...
Marco Prenassi +12 more
doaj +1 more source
Parainfectious Anti-Glial Fibrillary Acidic Protein-Associated Meningoencephalitis [PDF]
Movement disorders associated with glial fibrillary acidic protein (GFAP) autoantibodies have rarely been reported as ataxia or tremors. A 32-year-old man with headache and fever, initially diagnosed with viral meningoencephalitis, showed gradual ...
Jae Young Joo, Dallah Yoo, Tae-Beom Ahn
doaj +1 more source

