Another Microlesion Effect after STN‐DBS for Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Atsushi Umemura +3 more
wiley +1 more source
Preoperative Functional Connectivity Predicts Antiparkinson Drug Change after Deep Brain Stimulation
Abstract Background Deep brain stimulation (DBS) can effectively ameliorate motor symptoms in Parkinson's disease (PD), but patient outcomes remain variable. Clinical predictors lack reliability and only explain a small proportion of outcome variance, outlining a need for biomarkers that can enhance prediction accuracy.
David Mikhael +9 more
wiley +1 more source
High-Speed Videomicroscopy Analysis Presents Limitations in Diagnosis of Primary Ciliary Dyskinesia
Adam J. Shapiro +5 more
openalex +1 more source
Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi +6 more
wiley +1 more source
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger +1 more
wiley +1 more source
ANTIPSYCHOTIC-INDUCED EXTRAPYRAMIDAL SYMPTOMS AND TARDIVE DYSKINESIA: ANALYSIS BASED ON A SPONTANEOUS REPORTING SYSTEM DATABASE IN JAPAN [PDF]
Yosuke Saga +3 more
openalex +1 more source
Reduction of L-DOPA-induced dyskinesia in animal models of Parkinson disease [PDF]
openalex +1 more source
Expanding the Genetic and Phenotypic Spectrum of DYT‐VPS16: The Importance of Splice‐Site Variants
Abstract Background DYT‐VPS16, an early‐onset isolated dystonia caused by variants in the VPS16 gene, has been reported in fewer than 70 patients. Methods We explored the clinical and genotypic spectrum of DYT‐VPS16 by investigating early‐onset dystonia patients with VPS16 variants discovered in our large Biodatabank and through gene‐matching ...
Ana Westenberger +39 more
wiley +1 more source
Severity‐Based and Family‐Centered Approaches to Deep Brain Stimulation in GNAO1‐Related Disorders
Movement Disorders Clinical Practice, EarlyView.
Jana Domínguez‐Carral +1 more
wiley +1 more source
Loss-of-Function Mutations in LRRC6 , a Gene Essential for Proper Axonemal Assembly of Inner and Outer Dynein Arms, Cause Primary Ciliary Dyskinesia [PDF]
Esther Kott +18 more
openalex +1 more source

