Results 221 to 230 of about 79,054 (352)

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki   +4 more
wiley   +1 more source

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

open access: yesClinical Genetics, EarlyView.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart   +17 more
wiley   +1 more source

Novel homozygous <i>C3orf67</i> gene variant associated with primary ciliary dyskinesia in a Saudi pediatric patient: A case report. [PDF]

open access: yesWorld J Exp Med
Alkhadidi F   +7 more
europepmc   +1 more source

PERSISTENT DYSKINESIA AFTER LONG-TERM TREATMENT WITH NEUROLEPTICS IN JAPAN

open access: bronze, 1976
Gohei Yagi   +4 more
openalex   +2 more sources

Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2013
M. Knowles   +4 more
semanticscholar   +1 more source

Beyond bacteria and breaking the norm: Pulmonary mucormycosis due to <i>Absidia corymbifera</i> in a child with primary ciliary dyskinesia. [PDF]

open access: yesJ Int Med Res
Alghamdi AO   +10 more
europepmc   +1 more source

Implant Therapy in Patients With Neurodegenerative Diseases—A Scoping Review

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The increasing longevity of populations has resulted in a growing number of older adults requiring prosthodontic care, including those with neurodegenerative diseases (NDs). Neurodegenerative diseases pose significant challenges to prosthodontic care, and it remains unclear whether implant therapy in this population achieves ...
Lysandre David   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy