Results 71 to 80 of about 79,054 (352)

Copulatory Dyskinesia: Pathognomonic Manifestation of Tardive Dyskinesia

Tremor and Other Hyperkinetic Movements, 2020
Copulatory or pelvic thrusting dyskinesia is a subtype of tardive dyskinesia (TD) which is caused by exposure to dopamine blocking agents.A man exhibiting rhythmic, stereotypical pelvic thrusting movements.Recognition of copulatory dyskinesia as a distinctive iatrogenic disorder helps prevent unnecessary investigations and guides the implementation of ...
Sharma, Vibhash D., Gupta, Harsh V., Espay, Alberto J.   +2 more
openaire   +3 more sources

DOCK8 deficiency presenting with sclerosing cholangitis, raised immunoglobulin E, and bronchiectasis: A fatal pediatric case report

JPGN Reports, EarlyView.
Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou, Kelechi Ugonna, Stephen Hughes, Sanjay Rajwal, Marumbo Mtegha   +4 more
wiley   +1 more source

Effect of levodopa‐carbidopa intestinal gel on dyskinesia in advanced Parkinson's disease patients

Movement Disorders, 2016
The purpose of this study was to assess the effect of levodopa‐carbidopa intestinal gel (carbidopa‐levodopa enteral suspension) in advanced Parkinson's disease patients with troublesome dyskinesia.
A. Antonini, V. Fung, J. Boyd, J. Slevin, Coleen M Hall, K. Chatamra, S. Eaton, J. Benesh   +7 more
semanticscholar   +1 more source

Case series: Joubert syndrome and eosinophilic esophagitis

JPGN Reports, EarlyView.
Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening, Stephanie Leon‐Paredes, Eric Chiou, Vibha Szafron, Anthony Olive, Sara Anvari   +5 more
wiley   +1 more source

The Role of Primary Motor Cortex (M1) Glutamate and GABA Signaling in l-DOPA-Induced Dyskinesia in Parkinsonian Rats

Journal of Neuroscience, 2016
Long-term treatment of Parkinson's disease with l-DOPA almost always leads to the development of involuntary movements termed l-DOPA-induced dyskinesia. Whereas hyperdopaminergic signaling in the basal ganglia is thought to cause dyskinesia, alterations ...
David Lindenbach, M. Conti, C. Y. Ostock, Jessica A. George, A. A. Goldenberg, Mitchell Melikhov-Sosin, E. Nuss, C. Bishop   +7 more
semanticscholar   +1 more source

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma, Sushanth Neerumalla, Ali Baird, Russell A. Whitehead, Peter Filip, Bobby A. Tajudeen, Pete S. Batra, Peter Papagiannopoulos   +7 more
wiley   +1 more source

Tolcapone: review of its pharmacology and use as adjunctive therapy in patients with Parkinson's disease

Clinical Interventions in Aging, 2009
Daniel D TruongThe Parkinson’s and Movement Disorder Institute, Fountain Valley, CA, USAAbstract: Levodopa has been the gold standard therapy for the motor symptoms of Parkinson’s disease for more than three decades.
Daniel D Truong
doaj  

Early Dyskinesias in Parkinson’s Disease Patients With Parkin Mutation: A Primary Corticostriatal Synaptopathy?

Frontiers in Neuroscience, 2019
Mutations in the PARKIN gene cause early-onset Parkinson’s disease (PD). Despite the high proportion of still missing phenotyping data in the literature devoted to early-onset PD, studies suggest that, as compared with late-onset PD, PARKIN patients show
Jenny Sassone, Jenny Sassone, Flavia Valtorta, Flavia Valtorta, Andrea Ciammola   +4 more
doaj   +1 more source

Amantadine extended release for levodopa‐induced dyskinesia in Parkinson's disease (EASED Study)

Movement Disorders, 2015
ADS‐5102 is a long‐acting, extended‐release capsule formulation of amantadine HCl administered once daily at bedtime. This study investigated the safety, efficacy, and tolerability of ADS‐5102 in Parkinson's disease (PD) patients with levodopa‐induced ...
R. Pahwa, C. Tanner, R. Hauser, K. Sethi, S. Isaacson, D. Truong, Lynn K. Struck, A. Ruby, Natalie McClure, G. Went, M. Stempien   +10 more
semanticscholar   +1 more source

Elexacaftor–Tezacaftor–Ivacaftor Reduces Revision Sinus Surgery in People With Cystic Fibrosis

The Laryngoscope, EarlyView.
Elexacaftor–tezacaftor–ivacaftor (ETI) was associated with a significant decrease in the frequency and rate of endoscopic sinus surgeries in patients with cystic fibrosis. These findings suggest an improvement in CF‐related chronic rhinosinusitis outcomes following ETI and may influence future CF treatment decisions.
Amy Lin, Makanko Komara, Isaac Kistler, Zheng Hong Tan, Meredith Lind, Kavitha Kotha, Tendy Chiang   +6 more
wiley   +1 more source