Results 71 to 80 of about 20,538 (302)

Impulsivity Relates to Relative Preservation of Mesolimbic Connectivity in Patients with Parkinson Disease. [PDF]

, 2020
IntroductionThe relationship between Parkinson Disease (PD) pathology, dopamine replacement therapy (DRT), and impulse control disorder (ICD) development is still incompletely understood.
Bari, Ausaf, DiCesare, Jasmine, Hashoush, Nadia, Pouratian, Nader, Price, Collin, Riskin-Jones, Hannah, Sparks, Hiro   +6 more
core  

Motor complications in an incident Parkinson’s disease cohort [PDF]

, 2017
Acknowledgements We acknowledge funding for the PINE study from Parkinson's UK, the Scottish Chief Scientist Office, the BMA Doris Hillier Award, RS Macdonald Trust, the BUPA Foundation, NHS Grampian Endowments and SPRING. We thank the patients for their
Ahlskog, Caslake, Chapuis, Chondrogiorgi, Evans, Fahn, Fitzsimmons, Garcia-Ruiz, Gerpen, Hassin-Baer, Hauser, Hughes, Jankovic, Kipfer, Ku, Kumar, Marras, Mazzella, Mizuno, Noyce, Olanow, Parkinson Study Group, Parkinson Study Group CALM Cohort Investigators, Peduzzi, Rascol, Rybicki, Samii, Schrag, Sharma, Sharma, Smith, Stocchi, Taylor, Tomlinson, Wills, Zappia   +35 more
core   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Prevalence of Dyskinesia and OFF by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and OFF: Novel Analyses of Diary Data from Gocovri Pivotal Trials. [PDF]

, 2019
BACKGROUND: Parkinson\u27s disease (PD) patients using levodopa commonly develop dyskinesia and OFF episodes that reduce quality of life. OBJECTIVE: Evaluate prevalence of troublesome dyskinesia and OFF through the day, assessed by 30-minute intervals ...
Elmer, Lawrence W., Hauser, Robert A., Howard, Robert, Johnson, Reed, Kreitzman, David L., Kremens, Daniel, Nguyen, Jack T., Patni, Rajiv, Walsh, Ryan R.   +8 more
core   +1 more source

Levodopa-induced dyskinesia in Parkinson disease: Current and Evolving Concepts. [PDF]

, 2018
Levodopa‐induced dyskinesia is a common complication in Parkinson disease. Pathogenic mechanisms include phasic stimulation of dopamine receptors, nonphysiological levodopa‐to‐dopamine conversion in serotonergic neurons, hyperactivity of corticostriatal ...
Ahlskog, Ahmed, Alcacer, Antonini, Barnum, Bastide, Bez, Bezard, Bezard, Bordia, Calabresi, Calabresi, Carlsson, Carta, Cerasa, Cerasa, Cerasa, Cerasa, Cilia, Durif, Durif, Elia, Espay, Espay, Fahn, Fahn, Fasano, Feyder, Fieblinger, Fiorentini, Fox, Fox, Fox, Freitas, Fuente-Fernandez, Garcia, Gardoni, Gerlach, Goetz, Goetz, Grandas, Gray, Grondin, Herz, Herz, Herz, Huang, Hung, Huot, Iderberg, Jones, Katzenschlager, Kimber, Kishore, Kleiner-Fisman, Kosillo, Krack, Laere, Lau, Lee, Lee, Lim, Litim, Mansouri, Mellone, Meloni, Merola, Morgante, Morgese, Mura, Nadjar, Niccolini, Nicoletti, Nutt, Olanow, Olanow, Pahwa, Parkinson Study Group, Pavon, Picconi, Politis, Porras, Potts, Prescott, Rocha, Rosa, Rosa, Roussakis, Ruzicka, Samadi, Santini, Shen, Sierra, Smith, Stanic, Stathis, Stelt, Suarez, Svenningsson, Swann, Tanaka, Thiele, Tison, Trenkwalder, Verhagen Metman, Whone, Wichmann, Wood, Yamamura   +108 more
core   +1 more source

Frequency‐ and Network‐Specific Changes in Functional Connectivity Reflect Pathophysiological Mechanisms across Parkinson's Disease Stages

Annals of Neurology, EarlyView.
Objective Parkinson's disease (PD) is increasingly conceptualized as a disorder of large‐scale brain networks, yet whether and how frequency‐specific functional connectivity reorganizes across stages remains poorly understood. In this study, we used high‐density electroencephalography (EEG) to characterize cortico‐cortical functional connectivity ...
Matteo Conti, Valentina D'Onofrio, Luca Lorenzon, Laura Ludovica Grassi, Davide Mascioli, Valerio Ferrari, Clara Simonetta, Sofia Pavan, Francesca Di Giuliano, Mariangela Pierantozzi, Tommaso Schirinzi, Diego Centonze, Maurizio Corbetta, Angelo Antonini, Alessandro Stefani, Andrea Guerra   +15 more
wiley   +1 more source

Editorial: new advanced wireless technologies for objective monitoring of motor symptoms in Parkinson's disease [PDF]

, 2018
Nowadays, a growing number of researchers is using advanced wearable technologies with inertial measurement units (IMUs) to improve the evaluation of motor symptoms in patients with Parkinson’s Disease (PD).
Cabestany, Joan, Irrera, Fernanda, Suppa, Antonio   +2 more
core   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

MOVEMENT DISORDER CAUSED BY HYPEROSMOLR HYPERGLYCEMIC STATE IN AN OLDER ADULT: A CASE REPORT

Geriatrics, Gerontology and Aging, 2020
Diabetes mellitus (DM) and its complications constitute the leading causes of early mortality in most countries. Population aging and the growing prevalence of obesity and sedentary lifestyles, in addition to spreading urbanization, are considered the ...
Raíssa Katherine Rodrigues, Leandro Augusto Rocha, Marcelo Perim Baldo, Michelle Aparecida Ribeiro Borges, Ronaldo Urias Mendonça, Simone de Melo Costa, Luciana Colares Maia   +6 more
doaj   +1 more source

Uncontrollable movements of right upper and lower extremities in a child: A diagnostic puzzle

Journal of the American College of Emergency Physicians Open, 2021
We describe a case of a 9‐year‐old child who presented with uncontrollable, involuntary movements associated with a recent streptococcal infection and echocardiographic evidence of valvulitis.
Rucha Patki, Raquelle Douglas, Natalia Rimareva, Noah Kondamudi   +3 more
doaj   +1 more source