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Obesity and dyslipidemia

Metabolism, 2019
Obesity, a pandemic of the modern world, is intimately associated with dyslipidemia, which is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines. However, recent evidence suggests that obesity-induced dyslipidemia is not a unique pathophysiological entity, but rather has distinct characteristics depending on many ...
Vekić, Jelena   +4 more
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Obesity and Dyslipidemia

Current Atherosclerosis Reports, 2023
This article sumarizes pathopysiological consequencies between obesity and dyslipidemia and aims to bring some practical approach.Dyslipidemia is often present in individuals with obesity and simultaneusly, many obese individuals have lipid metabolism disorders. Especially the abdominal obesity increases the cardiometabolic risk because of the presence
Barbora Nussbaumerova, Hana Rosolova
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Costs of dyslipidemia

Expert Review of Pharmacoeconomics & Outcomes Research, 2003
Dyslipidemia has been recognized as an important risk-factor for the development of cardiovascular disease. The current, available therapies of dyslipidemia, their effectiveness, costs, cost-effectiveness and healthcare implications are discussed. At the present time, the lipid-lowering therapies are dominated by statins.
Hanna, Zowall, Steven A, Grover
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Diabetic dyslipidemia

Metabolism, 2014
Diabetic dyslipidemia is characterized by elevated fasting and postprandial triglycerides, low HDL-cholesterol, elevated LDL-cholesterol and the predominance of small dense LDL particles. These lipid changes represent the major link between diabetes and the increased cardiovascular risk of diabetic patients.
Liya, Wu, Klaus G, Parhofer
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Contraception and dyslipidemia

American Journal of Obstetrics and Gynecology, 1993
The risks of cardiovascular disease associated with dyslipidemia differ in women and men, being more strongly associated with triglyceride/high-density lipoprotein in middle-aged women than in men. Although the incidence of heart disease is lower in women because they live longer, over a lifetime, cardiovascular disease in women is equal to that in men,
R H, Knopp, J C, LaRosa, R T, Burkman
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Metabolomics in Dyslipidemia

2014
Hyperlipidemia is an important public health problem with increased incidence and prevalence worldwide. Current clinical biomarkers, triglyceride, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol lack the necessary specificity and sensitivity and only increase significantly after serious dyslipidemia ...
Hua, Chen   +4 more
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Dyslipidemias and Microcirculation

Current Pharmaceutical Design, 2018
Dyslipidemia is widely accepted as one of the major risk factors in cardiovascular disease mainly due to its contribution in the pathogenesis of atherosclerosis in medium-sized and large arteries. However, it has become increasingly accepted that high-cholesterol levels can also adversely affect the microvasculature prior to the development of overt ...
Teresa, Padró   +2 more
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Pharmacotherapy of Dyslipidemia

Cardiovascular Drugs and Therapy, 2001
Reducing elevated levels of low-density-lipoprotein cholesterol (LDL-C) significantly reduces the incidence of coronary heart disease (CHD) events and mortality in hypercholesterolemic patients. CHD risk reduction is proportional to LDL-C reduction. Despite this knowledge, many physicians are not applying existing treatment guidelines to the extent ...
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Obesity and dyslipidemia

Endocrinology and Metabolism Clinics of North America, 2003
The primary dyslipidemia related to obesity is characterized by increased triglycerides, decreased HDL levels, and abnormal LDL composition. Much work has been done to elucidate the pathogenesis of the dyslipidemia of obesity, which seems to be closely related to insulin resistance in obese individuals; however, more studies in humans are needed to ...
Barbara V, Howard   +2 more
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Treatment of Dyslipidemias

Endocrine Practice, 1996
To summarize recommended treatment strategies for various dyslipidemias.The basic pathways of lipoprotein metabolism are reviewed, and the potential for interventional alterations to correct specific dyslipidemias is outlined. Guidelines for treatment based on published clinical trials, including the consensus report of the National Cholesterol ...
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