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PCSK9 gene participates in the development of primary dyslipidemias
, 2021 Dyslipidemias are a group of diseases, which are characterized by abnormal blood concentrations of cholesterol, triglycerides and/or low-density lipoprotein-cholesterol (LDL-c).
Alpuche Osorno JJ +4 more
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Treatment of dyslipidemia [PDF]
F1000Prime Reports, 2014 Atherosclerotic cardiovascular disease (including coronary heart disease, stroke and peripheral arterial disease) is the leading cause of death globally. Abnormal blood lipids (dyslipidemia), smoking, and high blood pressure are responsible for more than 75% of cases.
Tonkin, Andrew, Byrnes, Allison
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Arquivos Brasileiros de Cardiologia, 2016 Lipoproteins constitute a set of proteins and lipids, organized to facilitate the transport of lipids through blood plasma. Elevated or decreased levels of these lipoproteins may be related to genetic alterations in 40% to 60% of cases.1 This fact explains why it is common to find lipid abnormalities in several members of the same family.
García-Giustiniani, Diego +1 more
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Indian Journal of Endocrinology and Metabolism, 2013 Atherogenic dyslipidemia (AD) refers to elevated levels of triglycerides (TG) and small-dense low-density lipoprotein and low levels of high-density lipoprotein cholesterol (HDL-C). In addition, elevated levels of large TG rich very low-density lipoproteins, apolipoprotein B and oxidised low-density lipoprotein (LDL), and reduced ...
C N Manjunath +3 more
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The Journal of Clinical Endocrinology & Metabolism, 2007 Recently, considerable progress has been made in understanding the genetic basis of dyslipidemias and in studying the safety and efficacy of lipid-lowering drugs for coronary heart disease (CHD) prevention. Novel loci have been identified for monogenic hypercholesterolemia, such as low-density lipoprotein (LDL) receptor (LDLR)-associated protein ...
Abhimanyu, Garg, Vinaya, Simha
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Evaluation of Lipid Profiles of Children and Youth from Basic Health Units in Campinas, SP, Brazil: A Cross-Sectional Laboratory Study [PDF]
Arquivos Brasileiros de CardiologiaBackground: Among dyslipidemias, hypercholesterolemia is considered the main risk factor for cardiovascular diseases in adults. In childhood and adolescence, elevated total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) are positively ...
Érica Ivana Lázaro Gomes +2 more
doaj +3 more sources
ChildrenFamilial hypercholesterolemia (FH) is a common genetic disorder with a fairly constant worldwide prevalence of 1 case per 311 individuals worldwide.
Maria Elena Capra +5 more
doaj +1 more source
Adipose Tissue Complexities in Dyslipidemias
, 2019 Adipose tissue is the largest organ in the human body and, in excess, contributes to dyslipidemias and the dysregulation of other vascular and metabolic processes.
Deborah R. Gustafson +1 more
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Plant Sterols and Stanols for Pediatric Patients with Increased Cardiovascular Risk
ChildrenThe atherosclerotic process begins in childhood and progresses throughout adult age. Hypercholesterolemia, especially familial hypercholesterolemia (FH) and metabolic dysfunctions linked to weight excess and obesity, are the main atherosclerosis risk ...
Cristina Pederiva +3 more
doaj +1 more source
Fatores nutricionais associados às dislipidemias em usuários de serviço de atenção primária à saúde.
Acta Médica Portuguesa, 2011 Dyslipidemias are relevant to public health because are one of the major risk factors for Non-Communicable Diseases and Disorders, especially cardiovascular diseases.Identify factors associated with dyslipidemias on users of Primary Health Care Center ...
Nathália Luíza Ferreira +3 more
doaj +1 more source