Results 141 to 150 of about 60,298 (302)

First‐in‐Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1617, a Cathepsin‐S Inhibitor, in Healthy Adult Subjects

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima   +9 more
wiley   +1 more source

Self-care strategies and sources of knowledge on menstruation in 12,526 young women with dysmenorrhea: A systematic review and meta-analysis

open access: yesPLoS ONE, 2019
Introduction: Dysmenorrhea (period pain) is common and affects around three quarters of all young women under the age of 25. The majority of young women, for a variety of reasons, think of period pain as ‘normal’ and something to be managed or endured ...
M. Armour   +7 more
semanticscholar   +1 more source

Prevalence, impact and treatment of primary dysmenorrhea in workers of an Academic and Research Institute

open access: yesMexican Journal of Medical Research ICSA, 2013
Dysmenorrhea is one of the cyclical processes in chronic pelvic pain. Dysmenorrhea in women causes a high psychosocial and economic impact. For this reason, we conducted a study to assess the prevalence, impact and use of drugs for the treatment of ...
Héctor A. Ponce-Monter   +8 more
doaj   +1 more source

Hubungan Pengetahuan Dengan Perilaku Penanganan Dismenore Di SMA Negeri 7 Manado [PDF]

open access: yes, 2014
Abstrack: Introduction adolescence is a period of transition from childhood to adult. In teenage girl there is a physical change in reproductive organs changes that characterized by menstruation.
Karundeng, M. (Michael)   +2 more
core  

Association of baseline characteristics with clinical outcomes of tirzepatide treatment in Japanese patients with obesity disease: A subgroup analysis of the SURMOUNT‐J trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1278-1287, February 2026.
Abstract Aims This analysis aimed to assess the influence of selected baseline factors on tirzepatide treatment response in Japanese patients with obesity disease. Materials and Methods This was a prespecified subgroup analysis of the SURMOUNT‐J trial.
Koutaro Yokote   +4 more
wiley   +1 more source

The Relationship Between Nutritional Status and the Incidence of Dysmenorrhea in Adolescent Girls: A Frequency Analysis Based on Nutritional Status Categories

open access: yesHealth Dynamics
Background: Dysmenorrhea is a common complaint that occurs during menstruation. The main research problem is that dysmenorrhea is often experienced by young women with high cases.
Lintang Dwi Ariyanty   +3 more
doaj   +1 more source

Intravascular Adenomyosis in a Cynomolgus Macaque (Macaca Fascicularis)

open access: yesJournal of Medical Primatology, Volume 55, Issue 1, February 2026.
ABSTRACT Intravascular adenomyosis was discovered in a cynomolgus macaque, a previously unreported presentation of adenomyosis in non‐human primates that points to vascular involvement in adenomyosis etiology. Uterus gross exam was unremarkable, but histologic examination revealed multifocal endometrial tissue intimately associated with large thin ...
Hannah M. Ruetten   +4 more
wiley   +1 more source

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