Results 41 to 50 of about 17,314 (205)

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

Animal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang, Yan Zan, Tiantian Ma, Xiaoquan Huang, Junwei Li, Liangjun Xia, Yuping Sa, Youbing Xia   +7 more
wiley   +1 more source

Hysteroscopy metroplasty for partial septate uterus: Just a matter of infertility?

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The primary objective of this study is to assess the impact of hysteroscopic metroplasty on symptom relief, including dysmenorrhea, dyspareunia, and menstrual blood flow in women with partial uterine septa (U2a class). Additionally, the study aims to investigate potential correlations between clinical and ultrasonographic ...
Alessandro Arena, Agnese Virgilio, Camilla Franceschini, Erika Bettiol, Pierandrea De Benedetti, Roberto Sardina, Giulia Cincotta, Eugenia Mantovani, Renato Seracchioli, Paolo Casadio   +9 more
wiley   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source

Ospemifene May Not Treat Vulvar Atrophy: A Report of Two Cases

Sexual Medicine, 2016
Introduction: Ospemifene (Osphena, Shionogi Inc, Florham, NJ, USA) is an estrogen agonist and antagonist approved by the U.S. Federal Drug Administration for the treatment of “moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due ...
Andrew T. Goldstein, MD, Michelle A. King, MSC   +1 more
doaj   +1 more source

Interrelationships among endometriosis-related pain symptoms and their effects on health-related quality of life: a sectional observational study [PDF]

Obstetrics & Gynecology Science, 2018
ObjectiveTo assess the correlation between different pain symptoms and different domains of women's health-related quality of life (HRQoL).MethodsSeventy-seven women with deep infiltrating endometriosis were successively enrolled between June 2011 and ...
Marlon de Freitas Fonseca, Lilian Carvalho Aragao, Felipe Ventura Sessa, Jose Anacleto Dutra de Resende, Claudio Peixoto Crispi   +4 more
doaj   +1 more source

Clinical Significance of a Pain Scoring System for Deep Endometriosis by Pelvic Examination: Pain Score

Diagnostics, 2023
Endometriosis-associated pain is an essential factor in deciding surgical indications of endometriosis. However, there is no quantitative method to diagnose the intensity of local pain in endometriosis (especially deep endometriosis).
Masao Ichikawa, Tatunori Shiraishi, Naofumi Okuda, Kimihiko Nakao, Yuka Shirai, Hanako Kaseki, Shigeo Akira, Masafumi Toyoshima, Yoshimitu Kuwabara, Shunji Suzuki   +9 more
doaj   +1 more source

Pelvic venous disorders in women: Diagnosis and management for gynecologists

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni, Inbar Friedman, Jessica Smith, Brian Liu, Mary Melchior, Andrew D. Brown   +5 more
wiley   +1 more source

Dyspareunia in women in preand postmenopausal period [PDF]

Гинекология, 2016
The article presents current views on the multiple pathogenetic mechanisms of development of dyspareunia in women in pre - and postmenopausal women with positions of biopsychosocial approach.
A I Fedorova
doaj  

Trauma, attachment style, and somatization: a study of women with dyspareunia and women survivors of sexual abuse

BMC Women's Health, 2018
Background Evidence points toward shared characteristics between female survivors of sexual abuse and women with dyspareunia. This study explored, for the first time, similarities and differences between women who were exposed to sexual abuse to those ...
Michal Granot, Yoram Yovell, Eli Somer, Ahuva Beny, Ronit Sadger, Ronit Uliel-Mirkin, Yaara Zisman-Ilani   +6 more
doaj   +1 more source