Results 71 to 80 of about 17,314 (205)

The Role of Vaginal Oestrogen Therapy in Postmenopausal Women With Pelvic Organ Prolapse: Does It Have Any Impact on Perioperative Outcomes? A Systematic Review of Randomised Controlled Trials

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pelvic organ prolapse (POP) affects up to 50% of postmenopausal women, negatively impacting sexual function and quality of life. While surgery remains the primary treatment, increasing attention has been given to perioperative vaginal oestrogen therapy and its potential impact on surgical outcomes.
Gilda Sicilia, Salvatore Giovanni Vitale, Maurizio Nicola D'Alterio, Stefania Saponara, Francesco Scicchitano, Anna Maria Fulghesu, Rossella E. Nappi, Stefano Angioni   +7 more
wiley   +1 more source

Women's and Health Care Professionals' Experiences of Discontinuing Hormone Replacement Therapy (HRT): A Systematic Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Hormone Replacement Therapy (HRT) is used to manage menopausal symptoms, particularly vasomotor symptoms (VMS). HRT prescribing rates are rising, but most women will eventually discontinue. Objectives To explore the experiences of women stopping HRT, why women restart HRT, and the HCPs advising them. Search Strategy Embase, MEDLINE,
Sarah Bunnewell, Sabrina Keating, Jo Parsons, Martha Hickey, Sarah Hillman   +4 more
wiley   +1 more source

Symptom Flares in Endometriosis: Burden, Self‐Management and Barriers to Care in a Cross‐Sectional Survey

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To explore the characteristics of symptom flares, individual experiences and behaviours during flares in people with endometriosis. Design Online questionnaire shared on patient support sites. Setting People with a confirmed or working diagnosis of endometriosis (a working diagnosis is given by clinicians based on symptoms/history ...
Lydia Coxon, Emma Evans, Francine Toye, Emma Cox, Katy Vincent   +4 more
wiley   +1 more source

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source

The effect of antioxidant supplementation on dysmenorrhea and endometriosis-associated painful symptoms: a systematic review and meta-analysis of randomized clinical trials [PDF]

Obstetrics & Gynecology Science
This study aimed to review randomized controlled trials (RCTs) investigating the effects of dietary antioxidant supplements on the severity of endometriosis-related pain symptoms.
Saeed Baradwan, Abdulrahim Gari, Hussein Sabban, Majed Saeed Alshahrani, Khalid Khadawardi, Ibtihal Abdulaziz Bukhari, Abdullah Alyousef, Ahmed Abu-Zaid   +7 more
doaj   +1 more source

Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management.
Janice Hoang, Kathryn Halliday, Deborah Allen, Wema Meranda Mtika, Eve Tranter, Grace Glover, Lynn Tatnell, Julia Hippisley‐Cox, Carol Coupland, Sarah Hillman, Jennifer Hirst   +10 more
wiley   +1 more source

Systemic Therapy Management Strategies for Early‐Stage Breast Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Advances in systemic therapy for early‐stage breast cancer in Australia highlight genomic‐guided decisions, subtype‐specific strategies, and emerging targeted and immunotherapies, shaping personalized and de‐escalated treatment approaches. ABSTRACT Breast cancer is the most common cancer among Australian women, with early‐stage disease (Stages I, II ...
Nicholas Zdenkowski, Rachel Dear, Sanjeev Kumar, Hilary Martin, Dhanusha Sabanathan, Stephen J. Luen, Belinda Yeo   +6 more
wiley   +1 more source

An open, single center, clinical investigation to evaluate the efficacy and safety of a non-hormonal vaginal moisturizer for the symptomatic treatment of vulvovaginal atrophy in postmenopausal woman

Gynecological Endocrinology
Objective To evaluate the efficacy and safety of a non-hormonal vaginal moisturizer in alleviating the clinical symptoms of vulvovaginal atrophy (VVA).Methods This was an observational, single center, open label study in which the investigational product
Manuel Sánchez-Prieto, Nicolás Mendoza, Peter Chedraui, Félix Lugo-Salcedo, Aida Serra-Ribas, Sonia Aladrén-Pérez, Javier Bustos-Santafé, Rafael Sánchez-Borrego   +7 more
doaj   +1 more source

Mechanically Supporting Uterosacral Ligaments for the Relief of Provoked Vulvodynia: A Randomized Pilot Trial

Journal of Pain Research, 2021
Matan Schonfeld,1 Peter Petros,2 Jacob Bornstein1,3 1Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel; 2University of Western Australia School of Mechanical and Chemical Engineering, Perth, WA, Australia; 3Department of Obstetrics and ...
Schonfeld M, Petros P, Bornstein J
doaj  

Central sensitization in patients with chronic pelvic pain resistant to hormonal therapy: A cross‐sectional study of prevalence and clinical correlates in a tertiary referral cohort

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In women with hormone‐resistant chronic pelvic pain, central sensitization is highly prevalent and independently associated with significant quality‐of‐life impairment and increased analgesic burden. These findings highlight the need for systematic screening of sensitization and trauma to optimize multidisciplinary management in specialized care ...
Hajar Alawadi, Marie Cid, Jérôme Delotte, Pierre‐Alexis Gauci   +3 more
wiley   +1 more source