What's New? Immunohistochemical biomarkers are increasingly used for the grading of cervical intraepithelial neoplasia (CIN); however, their clinical utility in the prediction of CIN2 regression is largely unexplored. Here, the authors analyzed the risk of CIN2 regression in relation to p16INK4a and HPVE4 immunohistochemistry in a large cohort of women
Rikke Damgaard+10 more
wiley +1 more source
Your Patella Dislocated: Will It Happen Again? Key Magnetic Resonance Imaging Differences Between Patients With Multiple Patellar Dislocations and Patients With a One-Time Patellar Dislocation. [PDF]
Brenner JD+8 more
europepmc +1 more source
Prognostic impact of p16 and high‐risk HPV DNA in ~1300 patients with vulvar cancer
What's New? Vulvar cancer (VSCC) is rare, and little is known about early prognostic factors that could contribute to an individualized treatment plan. About 30%–40% of VSCCs are associated with human papillomavirus (HPV). Here, the authors investigated the prognostic influence of p16 status in VSCC in a large cohort of 1300 patients.
Susanne K. Kjær+14 more
wiley +1 more source
Dysplasia of extraocular muscles presenting as orbital space-occupying lesions-an extremely rare disorder. [PDF]
Tang SY, Wang XJ, Han MY, Yan JH.
europepmc +1 more source
ADAR1 mRNA quantification for predicting HSIL in persons with HIV and abnormal anal cytology
What's New? This study introduces ADAR1 mRNA quantification as a promising biomarker for improving high‐grade squamous intraepithelial lesion (HSIL) prediction in HIV‐positive individuals with abnormal anal cytology. With 92% specificity, it reduces unnecessary high‐resolution anoscopies (HRA) by 77%, offering a more efficient and targeted screening ...
Melissa Bello‐Perez+15 more
wiley +1 more source
Surgical treatment of monostotic fibrous dysplasia of the proximal femur in children and adolescents: Observational European Paediatric Orthopaedic Society multicenter study. [PDF]
van Geloven TP+18 more
europepmc +1 more source
Abstract Objective Cervical cancer and its precursor are labeled as HIV indicator conditions, justifying the recommendation of HIV testing for all patients. This study aimed to assess the acceptance and patients' and gynecologists' perceptions on HIV testing in patients with cervical dysplasia at the colposcopy outpatient clinic in hospitals in the ...
R. L. O. van de Laar+9 more
wiley +1 more source
Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study. [PDF]
Gad A+9 more
europepmc +1 more source
Abstract Background OHVIRA syndrome, a urogenital malformation, lacks standardized management. Narrative reviews exist, but there is no a comprehensive meta‐analysis. Objectives The aim of this first systematic review and meta‐analysis is to evaluate the current literature and inform management strategies.
Emma Bonetti+8 more
wiley +1 more source
Hypernatremia, Hyperlipemia and Hemorrhagic Enteritis in a Hypodipsic Dog with Corpus Callosum Dysplasia. [PDF]
Giannuzzi P+6 more
europepmc +1 more source