Results 131 to 140 of about 23,872 (240)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

open access: yesAdvanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche   +21 more
wiley   +1 more source

Charting the translational pathway: ISSCR best practices for the development of PSC-derived therapies. [PDF]

open access: yesStem Cell Reports
Barry J   +53 more
europepmc   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng   +12 more
wiley   +1 more source

E-Banking - ηλεκτρονική τραπεζική

open access: yes, 2006
Η ανάπτυξη του Διαδικτύου και του Παγκόσμιου Ιστού, ως υποδομών παγκόσμιας επικοινωνίας και συναλλαγών, εγείρουν μια σειρά από κρίσιμα ερωτήματα για την εξέλιξη του τρόπου διαχείρισης, προώθησης και διανομής χρηματοπιστωτικών προϊόντων και υπηρεσιών. Οι ταχύτατες αλλαγές του οικονομικού περιβάλλοντος υπαγορεύουν την ανάγκη κάλυψης νέων καταναλωτικών ...
openaire   +1 more source

Generalized Mechanism Model for Ecosystem Hysteresis

open access: yesAdvanced Science, EarlyView.
A simplified model examines ecosystem transitions into alternative states after disturbances by leveraging positive and negative feedbacks. It identifies critical tipping points and quantifies hysteresis. Tests conducted on lakes, grasslands, and pitcher‐plant leaves align closely with empirical data and enable the prediction of recovery trajectories ...
Yanbin Hao   +9 more
wiley   +1 more source

E-Banking - ηλεκτρονική τραπεζική

open access: yes, 2002
Το διαδίκτυο παρέχει τη δυνατότητα αμφίδρομης επαφής μεταξύ ανθρώπων, επιχειρήσεων και οργανισμών και κατ’ αυτό τον τρόπο έχει γίνει ήδη μέρος της ζωής εκατομμυρίων πολιτών του πλανήτη μας και επηρεάζει ποικιλόμορφα πολλές από τις ανθρώπινες δραστηριότητες.
openaire   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

open access: yesAdvanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding   +5 more
wiley   +1 more source

Evaluating the Effect of Random Multi-Donor Pooling on the Nutritional Variability in Donor Human Milk Using Computer Modeling. [PDF]

open access: yesMatern Child Nutr
Smith RM   +9 more
europepmc   +1 more source

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