Results 111 to 120 of about 18,916,371 (333)

The Scottish adolescent e-cigarette user : profiling from the Scottish Adolescent Lifestyle and Substance Use Survey (SALSUS) [PDF]

open access: yes, 2017
Objectives: Profiling the Scottish adolescent e-cigarette user Study design: 283 state, independent and grant maintained schools participated in the Scottish Adolescent Lifestyle and Substance Use Survey (SALSUS) between September 2013 and 2014.
Currie, Dorothy, Kaufmann, N.
core   +2 more sources

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

open access: yesAdvanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang   +14 more
wiley   +1 more source

The impact of cigarette and e-cigarette use history on transition patterns: a longitudinal analysis of the population assessment of tobacco and health (PATH) study, 2013–2015

open access: yesHarm Reduction Journal, 2020
Background Population models have been developed to evaluate the impact of new tobacco products on the overall population. Reliable input parameters such as longitudinal tobacco use transitions are needed to quantify the net population health impact ...
Lai Wei   +6 more
doaj   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi   +12 more
wiley   +1 more source

A Photoswitchable HaloTag for Spatiotemporal Control of Fluorescence in Living Cells

open access: yesAngewandte Chemie, EarlyView.
Photoswitchable fluorophores are critical for advanced bioimaging. Here, we develop a photoswitchable self‐labeling HaloTag that can reversibly modulate the emission of a bound fluorogenic dye via a light‐induced conformational change. In living cells, this tunable chemigenetic system enables precise spatiotemporal activation and control of emitter ...
Franziska Walterspiel   +10 more
wiley   +2 more sources

Electronic cigarette use patterns and reasons for use among smokers recently diagnosed with cancer

open access: yesCancer Medicine, 2018
Many patients with cancer use electronic cigarettes (e‐cigarettes), yet little is known about patterns and reasons for use. Using cross‐sectional baseline data from a randomized controlled trial, we aimed to describe prevalence and correlates of e ...
Sara Kalkhoran   +5 more
doaj   +1 more source

A Middle School Program to Prevent E-Cigarette Use: A Pilot Study of “CATCH My Breath”

open access: yesPublic health reports (1974), 2020
Objectives: From 2017 to 2018, electronic cigarette (e-cigarette) use increased 78% among high school students and 48% among middle school students in the United States. However, few e-cigarette prevention interventions have been evaluated. We determined
S. Kelder   +5 more
semanticscholar   +1 more source

Perceptions of E-Cigarettes among Black Youth in California. [PDF]

open access: yes, 2017
Research suggests that Black youth are less likely to use e-cigarettes than their white counterparts, yet little is known as to why. We examined perceptions of e-cigarettes among Black young adults (ages 18-25) to explore the meanings these youth ascribe
Annechino, Rachelle   +3 more
core   +3 more sources

Smoking‐Induced STC2+ Tumor Cells Drive Tumor‐Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single‐Cell Transcriptomics

open access: yesAdvanced Science, EarlyView.
This study identifies a smoking‐induced mechanism in LSCC whereby nicotine activates the CHRNA5–JAK2/STAT3 axis to drive STC2 transcription. STC2 upregulates TGFBI, which interacts with endothelial ITGA5 to regulate vascular permeability and promote metastasis.
Yujie Shen   +5 more
wiley   +1 more source

Do Electronic Cigarettes Assist Motivated Smokers With Quitting?: A Secondary Analysis from a Community-Based Study [PDF]

open access: yes, 2016
Objective: This study investigated the association between electronic cigarette, or e-cigarette, use after cessation treatment and tobacco abstinence at 12 months. It also examined characteristics of e-cigarette users and reasons for use.
Curry, Elana
core  

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