Results 111 to 120 of about 147,051 (257)

Controlled Trial of Cervical Cancer Screening Frequency Among Human Papillomavirus Vaccinated Women II: Cervical Pre‐Cancer End‐Points by Specific Non‐Vaccine HPV Types

International Journal of Cancer, EarlyView.
ABSTRACT We conducted a controlled trial among 5626 early adolescent women vaccinated in 2007–2009 against human papillomavirus (HPV) types 16/18 to evaluate the impact of high‐intensity versus low‐intensity cervical screening, respectively at ages 22/25/28 and 28 years with squamous‐cell intraepithelial lesions (SILs) as the end‐point.
Matti Lehtinen, Mònica Ortega Llobet, Tiina Eriksson, Iacopo Baussano, Miriam Elfström, Mehran Ghaderi, Penelope Gray, Katja Harjula, Kaisa Heikkilä, Mari Hokkanen, Saara Kares, Camilla Lagheden, Pekka Nieminen, Anna Söderlund‐Strand, Joakim Dillner, Ville N. Pimenoff   +15 more
wiley   +1 more source

Epigenetic Predictors of Smoking: External Validation and Association With Smoking‐Related Cancer Risk

International Journal of Cancer, EarlyView.
ABSTRACT Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm‐based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm‐based smoking predictors in a large sample of middle‐aged and older Australians for (i) their accuracy and reliability, and (ii) their ...
Xiaoyu Fan, Danmeng Lily Li, Allison M. Hodge, Julie K. Bassett, Nina Afshar, Melissa C. Southey, Graham G. Giles, Roger L. Milne, Pierre‐Antoine Dugué   +8 more
wiley   +1 more source

Prospective Analysis of Breastfeeding History and Ovarian Cancer Risk: Results From the Ovarian Cancer Cohort Consortium

International Journal of Cancer, EarlyView.
ABSTRACT Breastfeeding has been found to be associated with decreased ovarian cancer risk, but prospective analyses are sparse and limited by insufficient sample sizes to assess associations by histotype and patient characteristics. To investigate the association between breastfeeding (ever/never, duration, and timing) and incident epithelial ovarian ...
Sable N. Fest, Allison F. Vitonis, Mary K. Townsend, Wenyi Fan, Brett M. Reid, Mollie E. Barnard, Amy Berrington, Gary E. Fraser, Montserrat Garcia‐Closas, Synnove F. Knutsen, James V. Lacey Jr, Roger L. Milne, Katie M. O'Brien, Jessica L. Petrick, Dale P. Sandler, Veronica Wendy Setiawan, Lynne R. Wilkens, Wei Zheng, Matthew B. Schabath, Holly R. Harris, Britton Trabert, Brooke L. Fridley, Nicolas Wentzensen, Kathryn L. Terry, Shelley S. Tworoger, Naoko Sasamoto   +25 more
wiley   +1 more source

Cancer in Seychelles: A Population‐Based Study on Incidence, Trends and Stage at Diagnosis (2005–2024)

International Journal of Cancer, EarlyView.
ABSTRACT Seychelles, the smallest country in Africa but with the highest GDP per capita, has experienced rapid socioeconomic development. We analysed 20‐year cancer incidence trends (2005–2024) using data from the Seychelles National Cancer Registry (SNCR).
Anne Finesse, Jolene Mondon, Emelyn Shroff, Jude Gedeon, Meggy Louange, Donald Maxwell Parkin   +5 more
wiley   +1 more source

Comparison of HPV Antibodies Measured Prior to Diagnosis of Anal, Cervical, Oropharyngeal, Penile and Vaginal Cancers in the HPV Cancer Cohort Consortium

International Journal of Cancer, EarlyView.
ABSTRACT Antibodies against HPV proteins can provide pre‐diagnostic information about cancer development. We described the prevalence of antibodies to proteins of oncogenic HPV types prior to diagnosis of HPV‐related cancers. We analysed pre‐diagnostic blood from 1700 participants with incident HPV‐related cancers (anal = 387, cervical = 274 ...
Justina Ucheojor Onwuka, Marie‐Pierre Nobels, Aimée R. Kreimer, Lea Schroeder, Aida Ferreiro‐Iglesias, Ilir Agalliu, Demetrius Albanes, Qiuyin Cai, Gypsyamber D'Souza, Neal D. Freedman, Graham G. Giles, Allan Hildesheim, Wen‐Yi Huang, Kristian Hveem, Hilde Langseth, Roger L. Milne, Eivind Ness‐Jensen, Nicolas F. Schlecht, Lesley F. Tinker, Giske Ursin, Kala Visvanathan, Sylvia Wassertheil‐Smoller, Stephanie J. Weinstein, Wei Zheng, Mari Nygard, Mattias Johansson, Tim Waterboer, Gary M. Clifford, Hilary A. Robbins   +28 more
wiley   +1 more source

Immune‐Related Prognostic Gene Identification in Lung Squamous Cell Carcinoma With the Cancer Genome Atlas Mining and Immunohistochemistry Validation

iNew Medicine, EarlyView.
ABSTRACT Objective In the cancer microenvironment, stromal and immune cells hold clinical importance. In lung squamous cell carcinoma (LSCC), the aim of this study was to find immune‐linked gene expression that has prognostic pertinence. Methods From the Cancer Genome Atlas, this study obtained the LSCC gene expression profile.
Weijia Jiang, Jing Xu, Wenwen Ma, Qingjie Zhu, Pawin Pongkorpsakol, Guoping Sun   +5 more
wiley   +1 more source

Growing Through It: A Longitudinal Examination of Body Dissatisfaction, Mental Health, and Resilience During Adolescence

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Research indicates adolescence, specifically puberty, is a critical period of psychological and physiological development. It is well known that body image is a key aspect of developmental psychology impacting mental health. Yet little is known about the buffering effects of resilience to moderate the relationship between body ...
Tiffany M. Stewart, Nicole Y. Wesley, Stephanie Broyles, Felicia Chaisson, Kelsey A. Varzeas, Amanda E. Staiano   +5 more
wiley   +1 more source

Who Knows Best What the Next Year Will Hold for You? The Validity of Direct and Personality‐based Predictions of Future Life Experiences Across Different Perceivers

European Journal of Personality, EarlyView., 2020
Abstract This study explored the validity of person judgements by targets and their acquaintances (‘informants’) in longitudinally predicting a broad range of psychologically meaningful life experiences. Judgements were gathered from four sources (targets, N = 189; and three types of informants, N = 1352), and their relative predictive validity was ...
Nele M. Wessels, Johannes Zimmermann, Daniel Leising, Jan‐Erik Lönnqvist   +3 more
wiley   +1 more source

High‐Content Screening Comparison of 1R6F Cigarette Smoke Extract and Selected Heated Tobacco and Electronic Vapour Product Aerosol Extracts in Endothelial and Bronchial Epithelial Cell Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Cigarettes induce oxidative stress and DNA damage, processes that contribute to cardiovascular and pulmonary disease. High content screening (HCS) is an increasingly valuable tool for comparative toxicology because it enables simultaneous quantification of multiple mechanistic endpoints at single‐cell resolution. In this study, HCS was used to
Edgar Trelles Sticken, Konstantinos Papikinos, Fiona Chapman, Roman Wieczorek, Sarah Jean Pour, Torge Evenburg, Sandra Otte, Tiandan Wu, Liam Simms, Matthew Stevenson   +9 more
wiley   +1 more source

Establishment and Application of a Quantitative Lipemia Index as a Novel Indicator for Assessing Lipemic Interference in Clinical Chemistry

Journal of Clinical Laboratory Analysis, EarlyView.
A rigorously validated quantitative lipemia index (LI) assay was established for direct serum turbidity measurement. This standardized LI metric demonstrated significantly stronger correlation with lipemic interference (rs = 0.822) than conventional triglyceride concentration (rs = 0.770), consistent with its direct measurement of optical turbidity ...
Haifeng Xie, Shuhua Bao, Pengcheng Tong, Peng Li, Zhe Shen, Jinlong Wei   +5 more
wiley   +1 more source