Results 291 to 300 of about 18,916,371 (333)

GNPAT/USP30 Stabilizes DRP1 Protein to Promote Mitochondrial Fission and Functional Damage in COPD Progression

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Our previous study revealed the role of glycerol phosphate O‐acyltransferase (GNPAT) in regulating chronic obstructive pulmonary disease (COPD). However, its further mechanisms remained unclear. In this study, COPD models were established by exposing mice to cigarette smoke particulates.
Xin‐Gui Cheng, Yun‐Chan Liu, Fei Chen, Ji‐Wei Li, Xiao‐Zhou Yao, Qing‐Yun Chen   +5 more
wiley   +1 more source

Initial Subjective Response to Nicotine Vaping Predicts Subsequent E-Cigarette Use in Early Adolescence: An ABCD Investigation. [PDF]

Nicotine Tob Res
Courtney KE, Nguyen-Louie TT, Thompson WK, Wade NE, Gonzalez MR, Jacobus J, Doran N.   +6 more
europepmc   +1 more source

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Nicotine in e-cigarette aerosol reduces GABA neuron migration via the α7 nicotinic acetylcholine receptor. [PDF]

Sci Rep
Parnell AA, McCarthy DM, Trupiano MX, Schatschneider C, Bhide PG.   +4 more
europepmc   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu, Wen‐Juan Wang, Ting‐Ting Zhang, Qi‐Chong Yang, Haliminai Dilimulati, Song‐Tao An   +5 more
wiley   +1 more source

Correlation between e-cigarette use and salivary flow rate, pH, and buffering capacity: a cross-sectional pilot study. [PDF]

BMC Oral Health
Alsenani M, Alothman L, Alsenaidi J, Alnowaiser A, Aldawsari M, Alharbi N.   +5 more
europepmc   +1 more source

The Malignant Transformation Rate of Oral Carcinoma In Situ

The Laryngoscope, EarlyView.
Oral carcinoma in situ (OCIS), where cancer cells are confined to the epithelium, is a Stage 0 malignant condition known to progress to invasive oral squamous cell carcinoma (OSCC). The rate and timeframe of this transformation are not well delineated.
Andrew Meci, Neerav Goyal, David Goldenberg   +2 more
wiley   +1 more source

Effectiveness and Safety of Dupilumab Monotherapy in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyps

The Laryngoscope, EarlyView.
In this phase 4, open‐label, single‐arm, multicenter study, dupilumab monotherapy was associated with reductions from baseline to week 24 (primary endpoint) in the bilateral endoscopic Nasal Polyp Score (NPS) in 25 Japanese adults with inadequately controlled chronic rhinosinusitis with nasal polyps on standard care therapies.
Shigeharu Fujieda, Tetsuji Takabayashi, Nobuo Ohta, Mamoru Yoshikawa, Yuki Kibe, Masato Ishida, Katsuhisa Suzuki, Yoshinori Takahashi, Nikhil Amin, Lakiea Wright, Lacey Robinson, Kenji Yahata   +11 more
wiley   +1 more source

Impact of product-based e-cigarette marketing on the attitudes and behavioural intentions of young Australians: an experimental study. [PDF]

Tob Control
Jongenelis MI, McCausland K, Bode S, Howard T, Ledger M, Durkin SJ.   +5 more
europepmc   +1 more source

Bridging the Ideological Divide: Advertising Strategies for Promoting Stigmatized Products

Psychology &Marketing, EarlyView.
ABSTRACT Many socially relevant sexual and reproductive health products remain stigmatized by some consumers due to enduring socio‐cultural taboos, despite broader acceptance by others. Such stigma limits product adoption and poses public health risks.
Yunlu Zhao, Verdiana Giannetti, Evangelia Mavroudi, Dayananda Palihawadana   +3 more
wiley   +1 more source