Results 71 to 80 of about 124,588 (267)

Associations of attitudes towards electronic cigarettes with advertisement exposure and social determinants: a cross sectional study

open access: yesTobacco Induced Diseases, 2017
Introduction The exposure of young adults to electronic cigarette (e-cigarette) advertisements has risen rapidly. E-cigarette ads have been shown to increase short term perceived acceptability of using e-cigarettes in places where traditional cigarettes ...
Benjamin Reinhold   +4 more
doaj   +1 more source

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

open access: yesAdvanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu   +20 more
wiley   +1 more source

An evaluation of school-based e-cigarette control policies’ impact on the use of vaping products

open access: yesTobacco Induced Diseases, 2018
Introduction Electronic cigarette (e-cigarette) use among youth is common, and so efforts to regulate its use and availability are continually being made.
Sandra Milicic   +3 more
doaj   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

open access: yesAdvanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin   +5 more
wiley   +1 more source

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

open access: yesAdvanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang   +13 more
wiley   +1 more source

Targeting Kynurenine Synthesis Attenuated Cigarette Smoke‐Induced COPD‐Like Lung Injury Driven by TALDO1‐Mediated Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Cigarette smoke induces airway epithelial TALDO1 upregulation and L‐kynurenine accumulation, driving mitochondrial injury with elevated mtROS, reduced Δψm, ATP, and OCR. This links to lung inflammation, alveolar destruction, and lung function damage, all attenuated by Epacadostat or Taldo1 reduction.
Wenjing Wang   +13 more
wiley   +1 more source

Perceived ease of flavored e-cigarette use and e-cigarette use progression among youth never tobacco users.

open access: yesPLoS ONE, 2019
BACKGROUND:There is an increased need to understand how e-cigarette flavors may contribute to e-cigarette uptake and use among youth. We examined the relationship between perceived ease of flavored e-cigarette use and e-cigarette use susceptibility and ...
Julia Cen Chen-Sankey   +2 more
doaj   +1 more source

Construction Trade Work Is Associated With Accelerated Decline in Kidney Function

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Construction workers are exposed to airborne particulates, organic solvents, and metals—agents linked to elevated risk of chronic kidney disease (CKD). Few studies have evaluated whether construction trade work is associated with longitudinal changes in estimated glomerular filtration rate (eGFR), a key indicator of kidney function.
Sammy Almashat   +5 more
wiley   +1 more source

Measuring Child Disadvantage: Comparing Multidimensional and Socioeconomic Approaches for Predicting Developmental Outcomes

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Robust measurement of disadvantage is essential to identifying and addressing inequities in children's development. We tested how a multidimensional framework of child disadvantage performed relative to a traditional socioeconomic position (SEP) approach to predict developmental outcomes.
Wei Hong   +7 more
wiley   +1 more source

Behavioral economic demand for cigarettes and e-cigarettes: A preliminary study comparing associations with use and switching behavior in adult cigarette smokers

open access: yesAddictive Behaviors Reports
Debate has ensued over whether e-cigarettes decrease cigarette use and/or whether more stringent cigarette regulations are necessary to foster complete switching to e-cigarettes.
Mari S. Gades   +9 more
doaj   +1 more source

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