Results 31 to 40 of about 21,843,584 (315)

Democratic Disagreements. A Book Review of \u3cem\u3eLived Democracy in Education. Young Citizens’ Democratic Lives in Kindergarten, School and Higher Education\u3c/em\u3e [PDF]

open access: yes, 2023
As the title Lived Democracy in Education suggests, the predominantly Norwegian writers of the book share a deep and robust vision of democracy. Drawing on deliberative democratic theory and many other theoretical perspectives, the authors blend theory ...
Helkala, Sonja   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Experience, Problems and Prospects of Practical Implementation of the Concept “Open Government” of the Russian Federation

open access: yesУправленческое консультирование, 2019
The author’s hypothesis investigated in this article is connected with the statement about the imbalance in the practical implementation of the principles and priorities of the concept of open government in Russia and the need to study the institutional ...
D. Yu. Desyatnichenko   +1 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The Internet as a Moral Mediator. The Quest for Democracy

open access: yestripleC: Communication, Capitalism & Critique, 2008
Recently the impressive growth of the Web, and the Internet in general, has been considered as a promise that may both challenge and boost our representation of democratic institutions.
Emanuele Bardone, Lorenzo Magnani
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Searching for the Path to a More Perfect Union. A Book Review of \u3cem\u3eEducating for Democracy\u3c/em\u3e [PDF]

open access: yes
Educating for Democracy presents Walter Feinberg’s vision for the democratic aims of education. Feinberg argues that the evolutionary nature of democracy should be met with a citizenry capable of critical reflection.
McCullough, Aaron   +3 more
core   +1 more source

Experience American science of communication for Ukraine in the field of information democracy

open access: yesАмериканська історія і політика, 2016
In the article the scientific exploration of American experts communication. Determined that communication integrates research and development experts in sociology, political science, art, ethnology, journalism, law, philosophy, psychology and others ...
Mytko Antonina
doaj   +1 more source

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