Results 101 to 110 of about 4,985,169 (245)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Investigaciones y Ensayos, 2014 La arquitectura hidráulica Inca posee magistrales ejemplos de trabajo sobre pendientes rocosas, sobre todo para las zonas de los Andes Centrales.
Marco A. Giovannetti, Rodolfo A. Raffino
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
De patrones a empresarios. El campo argentino en la primera mitad del siglo XX
Investigaciones y Ensayos, 2014 Este trabajo de investigación histórica se propone caracterizar las estrategias - en tanto técnicas al servicio de un objetivo individual o colectivo, público o privado - elaboradas, implementadas y asumidas por quienes habiéndose transformado de ...
Noemí M. Girbal-Blacha
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Investigaciones y Ensayos, 2014 El desarrollo de este ensayo apunta a la discusión sobre la desamortización y desvinculación de los bienes, iniciada a fines del siglo XVIII y profundizada durante el siglo XIX, en procura de expandir el mercado de tierras.
Héctor Omar Noejovich
doaj
Structures and Bioactivities of Six New Triterpene Glycosides, Psolusosides E, F, G, H, H1, and I and the Corrected Structure of Psolusoside B from the Sea Cucumber Psolus fabricii. [PDF]
Mar Drugs, 2019 Silchenko AS +9 more
europepmc +1 more source