Results 131 to 140 of about 7,276,793 (308)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
De patrones a empresarios. El campo argentino en la primera mitad del siglo XX
Investigaciones y Ensayos, 2014 Este trabajo de investigación histórica se propone caracterizar las estrategias - en tanto técnicas al servicio de un objetivo individual o colectivo, público o privado - elaboradas, implementadas y asumidas por quienes habiéndose transformado de ...
Noemí M. Girbal-Blacha
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Investigaciones y Ensayos, 2014 El desarrollo de este ensayo apunta a la discusión sobre la desamortización y desvinculación de los bienes, iniciada a fines del siglo XVIII y profundizada durante el siglo XIX, en procura de expandir el mercado de tierras.
Héctor Omar Noejovich
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Investigaciones y Ensayos, 2014 En este trabajo se analiza la legislación sobre la justicia de paz de la campaña de Buenos Aires entre 1854 y 1884, con el objetivo de estudiar el esfuerzo que realizó el gobierno central para fortalecer las instituciones en el ámbito rural como parte de
Marta Valencia
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source