Results 191 to 200 of about 4,985,169 (245)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The genome of an enigmatic sea urchin parasite Echinomermella matsi Jones & Hagen, 1987 resolves its place among other invertebrate parasitic nematodes. [PDF]

G3 (Bethesda)
Kirangwa J, King E, Collins J, Bates A, Blaxter M, Holovachov O.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Noncanonical NF-κB pathway driven inflammation across multiple cellular compartments identifies NIK as a therapeutic target for inflammatory bowel disease. [PDF]

Front Immunol
Xu H, Li D, Liang J, Adamson N, Scherl A, Zou L, Hu C, Storm EE, Cox CB, Johnson A, Keir ME, Zhang H, Hang S.   +12 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Aging Impairs Macrophage Phagocytosis Through Mitochondrial ROS-Induced Collagen Production. [PDF]

Aging Cell
Wang Y, Xu X, Shen N, Han P, Wu L, Jin Y, Sun Y, Xiao L, Li J, Wang L, Yang Y, Zhang Q, Chen W, Yu C, Wu B.   +14 more
europepmc   +1 more source

Tailoring e-Cigarette Health Messages by Vaping Status: How Source and Message Presentation Type Shape Young Adults' Perceptions. [PDF]

Nicotine Tob Res
Lee DN, Villanti AC, Stevens EM.
europepmc   +1 more source

Structures of protein folding intermediates on the ribosome. [PDF]

Nat Struct Mol Biol
Chan SHS, Streit JO, Włodarski T, Mitropoulou AN, Cassaignau AME, Bukvin IV, Waudby CA, Cabrita LD, Christodoulou J.   +8 more
europepmc   +1 more source

Combined electrospun fibre-microneedle patches for enhanced transmucosal delivery of benzodiazepines and proteins.

Biomater Sci
Berry C, Edmans JG, Slowik KM, Byers RA, Danby S, Hatton PV, Murdoch C, Colley HE.   +7 more
europepmc   +1 more source

Correction to "MIF-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Spinal Neurons and Microglial Polarization Facilitate Neuropathic Pain Progression". [PDF]

Anesthesiol Res Pract
europepmc   +1 more source