Results 221 to 230 of about 32,634,218 (335)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Risk prediction models for detecting a new diagnosis of heart failure within 5 years in the community: a systematic review. [PDF]

BMJ Open
Thaitirarot C, Sze S, Jones N, Barker J, Chan A, Hobbs FDR, Taylor KS, Taylor CJ.   +7 more
europepmc   +1 more source

Review: Principles of Environmental Science, by Kenneth E. F. Watt [PDF]

, 1974
Edward J. Kormondy
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Carboxyl-Terminal Region of the Maturation Protein of RNA Coliphage Qβ Mediates Host Attachment, Virion Formation, and Cell Lysis. [PDF]

Genes Cells
Kajitani M, Hakoshima N, Inokuchi Y.
europepmc   +1 more source

Brachystephanus glaberrimus: Luke, W.R.Q., Bangirinama, F., Beentje, H.J., Darbyshire, I., Gereau, R., Kabuye, C., Kalema, J., Kelbessa, E., Kindeketa, W., Minani, V., Mwangoka, M. & Ndangalasi, H.

, 2014
IUCN
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

In silico prediction, molecular docking and simulation of natural flavonoid apigenin and xanthoangelol E against human metapneumovirus. [PDF]

In Silico Pharmacol
Rahaman HH, Khan A, Sharif N, Ahmed W, Sharif N, Majumder R, Obregon SA, Iglesias RC, De la Torre Díez I, Dey SK.   +9 more
europepmc   +1 more source

Category F: Video Presentations (E‐Poster): Gynaecological Endoscopy and Robotic Surgery [PDF]

, 2018

openalex   +1 more source